Health-related Quality of Life of Patients With Chronic Systolic Heart Failure in Spain: Results of the VIDA-IC Study
Health-related Quality of Life of Patients With Chronic Systolic Heart Failure in Spain: Results of the VIDA-IC Study
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DOI：
10.1016/j.rec.2015.07.030
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发表时间：
2016-03-01
影响因子：
5.9
通讯作者：
Enjuanes, Cristina
中科院分区：
文献类型：
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作者：
Comin-Colet, Josep;Anguita, Manuel;Enjuanes, Cristina
简介和目标：尽管心力衰竭对西班牙患者的健康相关生活质量产生负面影响，但与此问题相关的临床因素的信息很少。方法：健康相关生活质量的横断面多中心研究。对 1037 名连续的收缩性心力衰竭门诊患者进行了专门问卷（堪萨斯城心肌病问卷）和通用问卷（EuroQoL-5D）。结果：大多数生活质量差的患者预后较差，心力衰竭严重程度增加。研究患者的活动能力受到更多限制，疼痛/不适和焦虑/抑郁的发生率高于一般人群和患有其他慢性病的患者。两份问卷的得分高度相关 (Pearson(R) = 0.815；P < .001）。多变量线性回归显示，年龄较大（标准化 beta = -0.2；P = .03）、女性（标准化 beta = -10.3；P < .001）、功能等级较差（标准化 beta = -20.4；P < .001）、查尔森合并症指数较高（标准化 beta = -1.2；P = .005）以及近期因心力衰竭住院（标准化 beta = 6.28；P = .006）是健康相关生活质量较差的独立预测因素。结论：心力衰竭患者的生活质量比一般西班牙人群和患有其他慢性疾病的患者差。女性、年龄较大、合并症、晚期症状和近期住院是这些患者健康相关生活质量的决定因素。 (C) 2015 年西班牙心脏病学会。由 Elsevier Espana, S.L.U. 出版版权所有。
Introduction and objectives: Although heart failure negatively affects the health-related quality of life of Spanish patients there is little information on the clinical factors associated with this issue.Methods: Cross-sectional multicenter study of health-related quality of life. A specific questionnaire (Kansas City Cardiomyopathy Questionnaire) and a generic questionnaire (EuroQoL-5D) were administered to 1037 consecutive outpatients with systolic heart failure.Results: Most patients with poor quality of life had a worse prognosis and increased severity of heart failure. Mobility was more limited and rates of pain/discomfort and anxiety/depression were higher in the study patients than in the general population and patients with other chronic conditions. The scores on both questionnaires were very highly correlated (Pearson(R) = 0.815; P < .001). Multivariable linear regression showed that being older (standardized beta = -0.2; P =.03), female (standardized beta = -10.3; P < .001), having worse functional class (standardized beta = -20.4; P < .001), a higher Charlson comorbidity index (standardized beta = -1.2; P = .005), and recent hospitalization for heart failure (standardized beta = 6.28; P = .006) were independent predictors of worse health-related quality of life.Conclusions: Patients with heart failure have worse quality of life than the general Spanish population and patients with other chronic diseases. Female sex, being older, comorbidity, advanced symptoms, and recent hospitalization are determinant factors in health-related quality of life in these patients. (C) 2015 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, S.L.U. All rights reserved.