Galanin stimulation of feeding is blocked by the addition of a response requirement.

Galanin stimulation of feeding is blocked by the addition of a response requirement.
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通过增加反应要求来阻止甘丙肽对进食的刺激。

DOI:
10.1037/0735-7044.122.4.949
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发表时间:
2008
影响因子:
1.9
通讯作者:
Robinson,JohnK
Robinson,JohnK
中科院分区:
医学4区
文献类型:
--
作者:
Brewer,Ariel;Robinson,JohnK

文献摘要

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在实验室大鼠和小鼠中,给药神经肽丙氨酸会增加食物摄入量,但这种增加只在自由喂养的条件下观察到。由于消费行为和工具性行为之间的差异越来越大,我们评估了甘丙氨酸是否会在食物是免费提供的或同样的食物是反应偶然的情况下不同地影响食物消费。我们还测试了在两种情况下,食物限制是否会与丙氨酸对食物消耗的影响相互作用。与之前的研究一样,在自由获取条件下,甘丙氨酸显著增加了食物消费量。然而,当食物取决于杠杆按压时,丙氨酸没有这种刺激作用。食物限制增加了两项任务的基础摄食水平,但食物限制与自由或反应性食物摄入之间没有相互作用。这些结果表明,甘丙肽诱导的喂养刺激仅限于自由获取的条件,并支持了完善行为和工具行为之间的理论区别。(PsycINFO数据库记录(c) 2016 APA,版权所有)
Administration of the neuropeptide galanin increases food intake in laboratory rats and mice, however this increase has only been observed under conditions of free-feeding. As there is a growing distinction between consummatory and instrumental behavior, we assessed whether galanin would differentially affect food consumption when food was freely available or when the same food was response-contingent. We also tested whether food restriction would interact with galanin's effect on food consumption in either condition. As in previous studies, galanin significantly increased food consumption under free access conditions. However, when food was contingent upon lever-pressing, galanin had no such stimulatory effect. Food-restriction increased basal feeding levels in both tasks but there was no interaction between food restriction and free or response-contingent food intake. These results demonstrate that galanin-induced feeding stimulation is limited to conditions of free access and support the theoretical distinction between consummatory and instrumental behavior.(PsycINFO Database Record (c) 2016 APA, all rights reserved)