RELATIONSHIP BETWEEN INTRAOCULAR-PRESSURE AND PRIMARY OPEN ANGLE GLAUCOMA AMONG WHITE AND BLACK-AMERICANS - THE BALTIMORE EYE SURVEY
RELATIONSHIP BETWEEN INTRAOCULAR-PRESSURE AND PRIMARY OPEN ANGLE GLAUCOMA AMONG WHITE AND BLACK-AMERICANS - THE BALTIMORE EYE SURVEY
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DOI：
10.1001/archopht.1991.01080080050026
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发表时间：
1991-08-01
影响因子：
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通讯作者：
SINGH, K
中科院分区：
文献类型：
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作者：
SOMMER, A;TIELSCH, JM;SINGH, K
在马里兰州东巴尔的摩进行的一项基于人群的患病率调查中，对5308名40岁及以上的黑人和白色受试者进行了详细的眼部检查，包括视野检查。 对选定的受试者进行了反复详细的检查。 大约有一半的原发性开角型青光眼视神经损伤的受试者，无论种族如何，都不知道他们有这种情况。 接受治疗的黑人青光眼患者的平均眼内压（IOP）几乎与未接受治疗的黑人患者相同（中位IOP，20 mm Hg）;白色患者的治疗眼的IOP低于未接受治疗的白色患者的眼（平均眼压[+/- SD]，18.69 +/- 3.23 mm Hg vs 24.15 +/- 5.23 mm Hg; P <0.001）。 青光眼性视神经损伤的风险随着筛选IOP的升高而增加，特别是在22 - 29和30 mm Hg及以上的水平（与IOP为15 mm Hg或更低相比，相对比率分别为12.8和40.1 mm Hg）。 无论是否接受治疗，超过一半的所有青光眼眼的筛选IOP低于21 mm Hg。 青光眼眼的IOP在随访时倾向于升高，而非青光眼眼的IOP可能升高也可能下降。 结果证实，IOP是青光眼的一个重要因素，但不支持“正常”和“升高”压力之间的传统区分，也不支持其推论，“低眼压”青光眼和“高眼压”青光眼。
A detailed ocular examination, including perimetry, was conducted on 5308 black and white subjects aged 40 years and older in a population-based prevalence survey in east Baltimore, Md. Repeated, detailed examinations were carried out on selected subjects. Roughly half of all subjects with optic nerve damage from primary open angle glaucoma, regardless of race, were unaware that they had the condition. The average intraocular pressure (IOP) among black patients with glaucoma who were receiving treatment was virtually identical to that in those black patients who were not receiving treatment (median IOP, 20 mm Hg); treated eyes of white patients had a lower IOP than those eyes of white patients who were not receiving treatment (mena [+/- SD] IOP, 18.69 +/- 3.23 mm Hg vs 24.15 +/- 5.23 mm Hg; P < .001). The risk of glaucomatous optic nerve damage increased with the height of the screening IOP, particularly at levels of 22 to 29 and 30 mm Hg and above (relative rate compared with IOP of 15 mm Hg or lower, 12.8 and 40.1 mm Hg, respectively). More than half of all glaucomatous eyes had a screening IOP below 21 mm Hg, whether these eyes were receiving treatment or not. The IOP in glaucomatous eyes tended to rise on follow-up, in contrast with nonglaucomatous eyes in which the IOP was as likely to rise as to fall. Results confirmed that IOP is an important factor in glaucoma, but did not support the traditional distinction between "normal" and "elevated" pressure, nor its corollaries, "low-tension" glaucoma and "high-tension" glaucoma.