Muscle strength assessments and the prevention of osteoporosis. A hypothesis.
Muscle strength assessments and the prevention of osteoporosis. A hypothesis.
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肌肉力量评估和骨质疏松症的预防。
DOI：
10.1111/j.1532-5415.1989.tb06686.x
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发表时间：
1989
影响因子：
6.3
通讯作者：
Sandler,RB
中科院分区：
文献类型：
--
作者：
Sandler,RB
预防措施，旨在终身保存骨骼的完整性，最好开始在成年早期，在显著的骨退化开始之前。早期干预将倾向于保持年轻成年期的PSM，从而为以后的岁月提供更大的保护余地，当年龄下降和卧床的可能性增加可能有害地影响骨骼平衡时。显然，在成年早期就开始预防的女性不能依赖雌激素替代疗法，而雌激素替代疗法是在绝经后预防性使用的，因为绝经前的机体充满了雌激素。因此，早期战略将不得不依赖于生活方式要素的改变。与这种策略相关的两个生活方式要素是钙的充分消耗和骨骼的适当机械负荷。钙在保持骨骼结构能力方面的重要性源于这样一个事实：按重量计算，矿物质构成了骨组织的三分之二，其中钙构成了约38%的恒定部分。6钙是a
Prophylactic measures, aimed at lifelong preservation of skeletal integrity should preferably be initiated in early adulthood, before the onset of significant bone decrements. Early intervention would tend to preserve the PSM of young adulthood, and thus provide a wider margin of protection for later years, when aging decrements and increased probabilities of confinement to bed may deleteriously affect skeletal balances. Clearly, prophylaxis initiated early in adulthood in women could not rely on estrogen replacement therapy, which is used prophylactically in postmenopausal years, because the premenopausal organism is estrogen-replete. Therefore, early strategy will have to rely on modifications of life-style elements. The two life-style elements that are relevant to such a strategy are adequate consumption of calcium and adequate mechanical loading of the bony skeleton.The importance of calcium in the preservation of structural competence of the skeleton stems from the fact that minerals constitute two-thirds of bone tissue by weight, of which calcium composes a constant fraction of about 38%. 6 Calcium is an obligatory participant in a