Characteristics of patients presenting with LUTS/BPH in six European countries
Characteristics of patients presenting with LUTS/BPH in six European countries
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DOI：
10.1016/j.eururo.2006.05.001
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发表时间：
2006-09-01
期刊：
影响因子：
23.4
通讯作者：
Dobronski, Piotr
中科院分区：
文献类型：
--
作者：
Hutchison, Annie;Farmer, Richard;Dobronski, Piotr
目的：了解下尿路症状/良性前列腺增生症(LUTS/BPH)人群的临床特征对卫生保健管理具有重要意义，这将影响人力需求、药物需求和卫生服务成本。通过跨尿路研究在初级卫生保健中提示BPH的LUTS管理政策的使用项目收集的数据，对来自6个欧洲国家的4979名新近出现LUTS/BPH的患者向全科医生或办公室泌尿科医生进行了描述。方法：在招募时，临床医生填写了一份问卷，详细说明了所提供的治疗、检查结果以及年龄、首发症状严重程度和合并症等协变量。患者完成了国际前列腺症状评分/生活质量问卷。结果：大多数患者(77%)因症状困扰而寻求医疗咨询，年龄在58岁至71岁之间。在初始症状严重程度、初始生活质量和确诊时年龄方面，不同国家之间存在微小但在统计学上显著的差异，但这些被认为没有临床意义。在患者管理方面存在明显的国家差异，例如，法国10%的患者报告没有进行检查，而波兰为0.5%，而自由流动测量结果在法国不到1%，在波兰为35%。结论：患者异质性不能解释各国住院患者管理的差异，这无疑是医疗传统、基础设施和社会经济因素以及患者偏好差异的结果。(C)2006年欧洲泌尿外科协会。爱思唯尔出版，版权所有。
Objectives: Knowledge of the clinical profile of the population with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) is important for health care management, impacting on manpower requirements, pharmacologic demands and health service costs. Data collected by the TransEuropean Research Into the Use of Management Policies for LUTS suggestive of BPH in Primary Health care project were used to profile 4979 patients from six European countries newly presenting with LUTS/BPH to general practitioners or office-based urologists.Methods: At recruitment, the clinician completed a questionnaire detailing the treatment provided, examination results, and covariates including age, initial symptom severity and comorbidities. The patient completed an International Prostate Symptom Score/quality-of-life questionnaire.Results: The majority of patients (77%) sought medical advice because of the bother-someness of their symptoms, and presented at ages between 58 and 71 years. Small but statistically significant differences among countries were found in initial symptom severity, initial quality of life and age at diagnosis, but these are not thought to be clinically significant. There were marked national differences in patient management, with, for example, 10% of patients in France reporting no examinations, compared with 0.5% in Poland, while free-flow measurements varied from less than 1% in France to 35% in Poland.Conclusions: Patient heterogeneity does not explain the differences inpatient management among countries, which undoubtedly is the result of differences in health care traditions, infrastructure and socioeconomic factors, as well as patient preference. (c) 2006 European Association of Urology. Published by Elsevier B.V. All rights reserved.