EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOID MALIGNANCIES: THE EXPANDING SPECTRUM OF HEMATOPOIETIC NEOPLASMS
EPSTEIN-BARR VIRUS-ASSOCIATED LYMPHOID MALIGNANCIES: THE EXPANDING SPECTRUM OF HEMATOPOIETIC NEOPLASMS
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DOI：
10.18999/nagjms.75.3-4.169
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发表时间：
2013-08
影响因子：
0.9
通讯作者：
H. Kimura;Jun-ichi Kawada;Yoshinori Ito
中科院分区：
文献类型：
--
作者：
H. Kimura;Jun-ichi Kawada;Yoshinori Ito
ABSTRACT Ubiquitous Epstein-Barr virus (EBV) infects not only B cells but also T and NK cells, and is associated with various lymphoid malignancies. The spectrum of EBV-associated lymphoid malignancies is expanding from Burkitt lymphoma to the newly defined systemic EBV+ T cell lymphoproliferative disease of childhood and hydroa vacciniforme-like lymphoma. However, some EBV-associated malignancies are not defined well and overlap other diseases. Furthermore, the role of EBV in tumorigenesis of lymphoid malignancies is still not clear. Further studies are necessary to clarify the pathogenesis of EBV-associated lymphoid malignancies for a better classification of each disease and for the establishment of effective treatment.
