Osteosarcoma: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

Osteosarcoma: ESMO Clinical Recommendations for diagnosis, treatment and follow-up
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DOI:
10.1093/annonc/mdp154
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发表时间:
2009-05-01
期刊:
影响因子:
50.5
通讯作者:
Casali, P. G.
Casali, P. G.
中科院分区:
医学1区
文献类型:
--
作者:
Bielack, S.;Carrle, D.;Casali, P. G.

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骨肉瘤是最常见的原发性骨癌(发病率:0.2–3/100 000/年)。青少年的发病率较高(15-19 岁每年为 0.8-11/100 000),占所有实体癌的 10% 以上。男女比例约为1.4。它通常出现在四肢长骨的干骺端,最常见于膝盖周围。主要在成人中观察到轴骨或颅面骨的受累。
Osteosarcoma is the most frequent primary cancer of bone (incidence: 0.2–3/100 000/year). The incidence is higher in adolescents (0.8–11/100 000/year at age 15–19), where it accounts for> 10% of all solid cancers. The male: female ratio is∼ 1.4. It usually arises in the metaphysis of a long extremity bone, most commonly around the knee. Involvement of the axial skeleton or craniofacial bones is observed primarily in adults.