New strategies for massive transfusion in the bleeding trauma patient.
New strategies for massive transfusion in the bleeding trauma patient.
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DOI：
10.1097/jtn.0b013e318256293e
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发表时间：
2012-04-01
期刊：
影响因子：
--
通讯作者：
Pritts, Timothy A
中科院分区：
文献类型：
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作者：
Davis, Dawn T;Johannigman, Jay A;Pritts, Timothy A
创伤仍然是40岁以下者的主要死亡原因。在最初24小时内死亡的主要原因是出血。这些患者中的许多存在严重的凝血病，需要大量输血。早期控制凝血病已被证明可以提高生存率。为了更快地解决凝血障碍，我们识别和复苏失血性创伤患者的方式发生了变化。这些变化包括早期识别高危患者和早期积极输注血浆和血小板。本文就损伤控制复苏的关键性大量输血触发因素和复苏策略进行综述。
Trauma continues to be the leading cause of death among those younger than 40 years. A major cause of death within the first 24 hours is hemorrhage. Many of these patients present with severe coagulopathy and require massive transfusion. Earlier control of coagulopathy has been shown to improve survival. To address coagulopathy sooner, changes in the way we identify and resuscitate the exsanguinating trauma patient have evolved. These changes include early identification of at-risk patients and early, aggressive transfusion of plasma and platelets. This article reviews the key massive transfusion triggers and resuscitation strategy of damage control resuscitation.