Quantification of Cardiorespiratory Fitness in Healthy Nonobese and Obese Men and Women
Quantification of Cardiorespiratory Fitness in Healthy Nonobese and Obese Men and Women
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DOI：
10.1378/chest.11-1147
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发表时间：
2012-04-01
期刊：
影响因子：
9.6
通讯作者：
Babb, Tony C.
中科院分区：
文献类型：
--
作者：
Lorenzo, Santiago;Babb, Tony C.
Background: The quantification and interpretation of cardiorespiratory fitness CRF in obesity is important for adequately assessing cardiovascular conditioning, underlying comorbidities, and properly evaluating disease risk. We retrospectively compared peak oxygen uptake ((V) over dot o(2)peak) (ie, CRF) in absolute terms, and relative terms (To predicted) using three currently suggested prediction equations (Equations R, W, and G).Methods: There were 19 nonobese and 66 obese participants. Subjects underwent hydrostatic weighing and incremental cycling to exhaustion. Subject characteristics were analyzed by independent t test, and % predicted ((V) over dot o(2)peak) by a two-way analysis of variance (group and equation) with repeated measures on one factor (equation).Results: ((V) over dot o(2)peak) (L/min) was not different between nonobese and obese adults (2.35 +/- 0.80 [SD] vs 2.39 +/- 0.68 L/min). ((V) over dot o(2)peak) was higher (P < .02) relative to body mass and lean body mass in the nonobese (34 +/- 8 mL/min/kg vs 22 +/- 5 mL/min/kg, 42 +/- 9 mL/min/lean body mass vs 37 +/- 6 mL/min/lean body mass). Cardiorespiratory fitness assessed as % predicted was not different in the nonobese and obese (91% +/- 17% predicted vs 95% +/- 15% predicted) using Equation R, while using Equation W and G, CRF was lower (P < .05) but within normal limits in the obese (94 +/- 15 vs 87 +/- 11; 101% +/- 17% predicted vs 90% +/- 12% predicted, respectively), depending somewhat on sex.Conclusions: Traditional methods of reporting ((V) over dot o(2)peak) do not allow adequate assessment and quantification of CRF in obese adults. Predicted ((V) over dot o(2)peak) does allow a normalized evaluation of CRF in the obese, although care must be taken in selecting the most appropriate prediction equation, especially in women. in general, otherwise healthy obese are not grossly deconditioned as is commonly believed, although CRF may be slightly higher in nonobese subjects depending on the uniqueness of the prediction equation. CHEST 2012; 141(4):1031-1039
