Przerzuty nowotworowe do jam nosa i zatok przynosowych z narządów odległych Distant metastases to nasal cavities and paranasal sinuses, from the organs outside the head and neck

Przerzuty nowotworowe do jam nosa i zatok przynosowych z narządów odległych Distant metastases to nasal cavities and paranasal sinuses, from the organs outside the head and neck
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从头颈部以外的器官远处转移到鼻腔和鼻旁窦

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发表时间:
2008
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通讯作者:
S. Bień
S. Bień
中科院分区:
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作者:
Joanna Kobiorska;S. Bień

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导言。锁骨下至头颈部的转移瘤相对少见,通常在原发病进展时出现。此时,正确的诊断只需要将初次活检的病理报告与头部和颈部肿块的活检进行比较。大多数头颈部的远处转移位于淋巴结内。鼻腔及副鼻窦的转移是非常罕见的,通常位于上颌窦内。材料46例头颈部远处转移瘤中,4例局限于鼻腔鼻窦,均在我科诊治。ORL HN与结肠癌蝶窦转移有关(作为本病的首发症状)。病人接受姑息性治疗,在确诊后2个月内死亡。案例二. M. 69岁,肾癌(Ca clarocellulare)转移到鼻腔,由于多发性肺转移,处于疾病的姑息期。由于疾病的广泛化,患者接受了多个疗程的化疗。鼻腔转移瘤采用多次局部切除治疗。目前头颈部无转移-存活,状况相对良好,观察23个月。三.国际刑事法院F.乳腺癌姑息期50年,骨和肝转移,上颌窦转移。接受姑息治疗。转移区域的治疗。诊断为上颌窦转移后5个月死亡。案例四. F. 54岁,结肠癌姑息期,肺部和肝脏多处转移;上颌窦转移。在血液治疗过程中出现上颌窦肿瘤症状,确认为转移。转移灶的姑息性Rtg治疗。18个月后死亡,诊断为上颌窦转移。结论.从远处器官转移到鼻腔和鼻窦的预后是悲惨的。在大多数鼻和鼻窦的远处转移中,姑息治疗是唯一可能的治疗选择。Hasla indek s owe:przerzuty nowotwowe jamy nosa,zatoki przynosowe K e y words:metastasis,nasal cavities,parasonal sinuses
Summary Introduction. The metastases from below the clavicles, to the head and neck region, are relatively uncommon, and usually dem- onstrate during the progression of the primary disease. At that time, the correct diagnosis requires only to compare the pathology report from the primary biopsy, with the biopsy from the lump in the head and neck. The majority of distant metastases to the head and neck region are localized within the lymph nodes. The metastases to nasal cavity and paranasal sinuses are very rare and usually localized within the maxillary sinus. Material. 4 cases, out of 46 all distant metastases to the head and neck region, localized in the nasal cavity and paranasal sinuses, diagnosed and treated in Dept. of ORL HN the metastasis of colonic carcinoma to the sphenoid sinus (as a fi rst symptom of the disease). The palliative Rtg-therapy was applied, and patient died in 2 months after diagnosis was established. Case II. M. 69 y with metastasis of kidney cancer (Ca clarocellulare) to the nasal cavity, during a palliative stage of the disease due to multiple lung metastases. Patient was treated with multiple courses of chemotherapy due to generalization of the disease. The nasal cavity metastasis was treated with repeated local resections. At present with no metastasis within the head and neck region - alive, in relatively good condition, with 23 months of observation. Cases III. F. 50 years in palliative stage of the breast cancer, with metastases to the bones and hepar and with metastasis to the maxillary sinus. Received palliative Rtg. therapy on the region of metastasis. Died in 5 months after diagnosis of maxillary sinus metastasis. Case IV. F. 54 years in palliative stage of the colonic cancer, with multiple metastases to the lungs and hepar; with metastasis to the maxillary sinus. During hemotherapy a symptoms of tumor of the maxillary sinus appeared, confi rmed as a metastasis. The palliative Rtg-therapy on the region of metastasis. Died in 18 months, after diagnosis of maxillary sinus metastasis. Conclusions. The prognosis of metastases from distant organs, to the nasal cavity and paranasal sinuses is miserable. In the majority of distant metastases to the nose and paranasal sinuses, the palliative therapy is the only possible option of treatment. Hasla indek s owe: przerzuty nowotworowe jamy nosa, zatoki przynosowe K e y words: metastases, nasal cavities, paranasal sinuses