Gaze-Centered Updating of Visual Space in Human Parietal Cortex

Gaze-Centered Updating of Visual Space in Human Parietal Cortex
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DOI:
10.1523/jneurosci.23-15-06209.2003
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发表时间:
2003-07
期刊:
The Journal of Neuroscience
影响因子:
--
通讯作者:
W. Medendorp;Herbert C. Goltz;T. Vilis;J. Crawford
W. Medendorp;Herbert C. Goltz;T. Vilis;J. Crawford
中科院分区:
其他
文献类型:
--
作者:
W. Medendorp;Herbert C. Goltz;T. Vilis;J. Crawford

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单单元记录已经确定了猴子后顶叶皮层(PPC)中的一个区域,该区域在以凝视为中心的框架中表示和更新视觉空间。在这里,使用事件相关的功能磁共振成像,我们确定了一个类似的双边地区在人类PPC显示对侧地形记忆引导的眼球运动和手臂运动。此外,当眼球运动逆转记忆中的水平目标位置相对于注视点,这个PPC区域交换活动的两个皮质小叶。这表明人类PPC动态更新以凝视为中心的框架中的空间行动目标。
Single-unit recordings have identified a region in the posterior parietal cortex (PPC) of the monkey that represents and updates visual space in a gaze-centered frame. Here, using event-related functional magnetic resonance imaging, we identified an analogous bilateral region in the human PPC that shows contralateral topography for memory-guided eye movements and arm movements. Furthermore, when eye movements reversed the remembered horizontal target location relative to the gaze fixation point, this PPC region exchanged activity across the two cortical lobules. This shows that the human PPC dynamically updates the spatial goals for action in a gaze-centered frame.