Three-dimensional multiexcitation magnetoacoustic tomography with magnetic induction.
Three-dimensional multiexcitation magnetoacoustic tomography with magnetic induction.
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DOI：
10.1063/1.3526001
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发表时间：
2010-12
影响因子：
3.2
通讯作者：
Xu Li;L. Mariappan;B. He
中科院分区：
文献类型：
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作者：
Xu Li;L. Mariappan;B. He
磁感应磁声层析成像（MAT-MI）是一种用于高空间分辨率生物组织电导率对比成像的混合成像方式。这种模式通过基于洛伦兹力的耦合机制将磁激励与超声检测结合起来。然而，以往的研究表明，单一类型磁激励的MAT-MI方法只能重建样品的电导率边界。为了实现更完整的电导率对比重建，我们提出了一种多激励MAT-MI方法。在该方法中，使用不同线圈配置的多个磁激励依次施加到物体上，并收集每个激励对应的超声信号进行电导率图像重建。在这项研究中，我们通过计算机模拟和模拟实验验证了新的多激励MAT-MI方法用于三维（3D）电导率成像。利用声波聚焦和柱面扫描两种磁激励方式获得三维体数据。仿真和实验结果表明，在有限带宽的普通超声探头下，我们能够正确地重建成像物体的三维相对电导率对比度。与以往单激发MAT-MI生成的电导率边界图像相比，新的多激发MAT-MI方法提供了更完整的电导率对比重建，因此在可能的临床和研究应用中提供了更有价值的信息。
Magnetoacoustic tomography with magnetic induction (MAT-MI) is a hybrid imaging modality proposed to image electrical conductivity contrast of biological tissue with high spatial resolution. This modality combines magnetic excitations with ultrasound detection through the Lorentz force based coupling mechanism. However, previous studies have shown that MAT-MI method with single type of magnetic excitation can only reconstruct the conductivity boundaries of a sample. In order to achieve more complete conductivity contrast reconstruction, we proposed a multiexcitation MAT-MI approach. In this approach, multiple magnetic excitations using different coil configurations are applied to the object sequentially and ultrasonic signals corresponding to each excitation are collected for conductivity image reconstruction. In this study, we validate the new multiexcitation MAT-MI method for three-dimensional (3D) conductivity imaging through both computer simulations and phantom experiments. 3D volume data are obtained by utilizing acoustic focusing and cylindrical scanning under each magnetic excitation. It is shown in our simulation and experiment results that with a common ultrasound probe that has limited bandwidth we are able to correctly reconstruct the 3D relative conductivity contrast of the imaging object. As compared to those conductivity boundary images generated by previous single-excitation MAT-MI, the new multiexcitation MAT-MI method provides more complete conductivity contrast reconstruction, and therefore, more valuable information in possible clinical and research applications.