Does major depression result in lasting personality change?
Does major depression result in lasting personality change?
复制标题
重度抑郁症会导致持久的性格改变吗？
DOI：
10.1176/ajp.153.11.1404
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Keller,MB
中科院分区：
文献类型：
--
作者：
Shea,MT;Leon,AC;Mueller,TI;Solomon,DA;Warshaw,MG;Keller,MB
有抑郁症史的人的特征是某些人格特质的高水平，特别是神经质，内向和人际依赖。作者检验了”疤痕假说”，即重性抑郁症发作导致持久的人格变化的可能性，这种变化持续到抑郁症康复之后。在两个不同的时间点对来自国家精神卫生研究所抑郁心理生物学合作项目的先证者样本进行评估间隔6年。与前瞻性观察的第一次发作的严重抑郁症在此期间的主题进行了比较，主题保持良好的变化，从时间1到时间2的自我报告的人格特质。所有的研究对象都很好（没有精神障碍），在两个assessment.ResultsThere的时候，没有证据表明，从发病前到发病后的评估中的任何人格特征的受试者与前瞻性观察的第一次发作的严重抑郁症在间隔的负面变化。结果表明，一个可能的关联的数量和长度的情节增加水平的情感依赖和内向，respectively.ConclusionsThe研究结果表明，自我报告的人格特质不改变后，一个典型的情节严重抑郁症。未来的研究需要确定这种变化是否发生在更严重，慢性或复发性抑郁症发作后。
ObjectiveIndividuals with a history of depression are characterized by high levels of certain personality traits, particularly neuroticism, introversion, and interpersonal dependency. The authors examined the" scar hypothesis," ie, the possibility that episodes of major depression result in lasting personality changes that persist beyond recovery from the depression.MethodA large sample of first-degree relatives, spouses, and comparison subjects ascertained in connection with the proband sample from the National Institute of Mental Health Collaborative Program on the Psychobiology of Depression were assessed at two points in time separated by an interval of 6 years. Subjects with a prospectively observed first episode of major depression during the interval were compared with subjects remaining well in terms of change from time 1 to time 2 in self-reported personality traits. All subjects studied were well (had no mental disorders) at the time of both assessments.ResultsThere was no evidence of negative change from premorbid to postmorbid assessment in any of the personality traits for subjects with a prospectively observed first episode of major depression during the interval. The results suggested a possible association of number and length of episodes with increased levels of emotional reliance and introversion, respectively.ConclusionsThe findings suggest that self-reported personality traits do not change after a typical episode of major depression. Future studies are needed to determine whether such change occurs following more severe, chronic, or recurrent episodes of depression.