An introduction to PET-CT imaging
An introduction to PET-CT imaging
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DOI：
10.1148/rg.242025724
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发表时间：
2004-03-01
期刊：
影响因子：
5.5
通讯作者：
Torok, FS
中科院分区：
文献类型：
--
作者：
Kapoor, V;McCook, BM;Torok, FS
癌症是发达国家如美国发病率和死亡率的主要原因之一。关于肿瘤患者的治疗的复杂临床决策在很大程度上由成像结果以及其他因素指导。大多数放射学程序映射肿瘤的解剖和形态，很少或没有关于其代谢的信息。使用2- [氟-18]氟-2-脱氧-D-葡萄糖（FDG）进行的正电子发射断层扫描（PET）已被证明在提供重要的肿瘤相关定性和定量代谢信息方面具有价值，这些信息对诊断和随访至关重要。PET-计算机断层扫描（CT）是CT提供的横截面解剖信息和PET提供的代谢信息的独特组合，这些信息在单次检查期间采集并融合。FDG PET-CT与单独使用PET相比具有几个优势;最重要的是能够准确地将增加的FDG活性定位到特定的正常或异常解剖位置，这可能很难甚至不可能单独使用PET。了解FDG PET-CT的原理和最佳扫描技术，并认识到潜在的缺陷和局限性，对于有利地使用这种成像方式是很重要的。
Cancer is one of the leading causes of morbidity and mortality in developed countries such as the United States. Complex clinical decisions about treatment of oncologic patients are largely guided by imaging findings, among other factors. Most radiologic procedures map the anatomy and morphology of tumors with little or no information about their metabolism. Positron emission tomography (PET) performed with 2- [fluorine-18] fluoro-2-deoxy-D-glucose (FDG) has proved valuable in providing important tumor-related qualitative and quantitative metabolic information that is critical to diagnosis and follow-up. PET-computed tomography (CT) is a unique combination of the cross-sectional anatomic information provided by CT and the metabolic information provided by PET, which are acquired during a single examination and fused. FDG PET-CT offers several advantages over PET alone; the most important is the ability to accurately localize increased FDG activity to specific normal or abnormal anatomic locations, which may be difficult or even impossible with PET alone. Understanding the principles of FDG PET-CT and the optimal scanning techniques and recognizing the potential pitfalls and limitations are important for advantageous use of this imaging modality.