LOFA: software for individualized localization of functional MRI activity.
LOFA: software for individualized localization of functional MRI activity.
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LOFA：用于功能性 MRI 活动个性化定位的软件。
DOI：
10.1006/nimg.1999.0511
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Bobholz,JA
中科院分区：
文献类型：
--
作者：
Gokcay,D;Mohr,CM;Crosson,B;Leonard,CM;Bobholz,JA
Although PET, SPECT, and fMRI studies have led to significant advances in functional mapping of the human brain, precise localization and quantification of activity in individual brains require additional procedures. Difficulties to be addressed by a localization strategy are: resolution of individual anatomic differences, differentiation of functional activity in closely juxtaposed brain regions, and management of multiple intricately shaped 3D anatomic structures. In this paper, we describe a localization tool, LOFA, which addresses these problems by forming ROIs with a user-driven interface. Using LOFA, complex 3D anatomy can be defined through open or closed loops and anatomic landmarks. Resulting partitions can be overlaid on top of each other to form multiple regions of interest (ROIs), and functional activity in these ROIs can be extracted individually, one after the other. LOFA introduces important paradigmatic advances over the other ROI analysis methods. The toolbox is interactive, fully compatible with AFNI (MCW), and requires Pv-Wave (VNI Inc.) license to run.
