Involvement of NMDAR 2 A tyrosine phosphorylation in depression-related behavior

Involvement of NMDAR 2 A tyrosine phosphorylation in depression-related behavior
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DOI:
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发表时间:
2009
期刊:
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影响因子:
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通讯作者:
S. Taniguchi;A. Tanimura;Y. Kiyama;T. Tezuka;A. M. Watabe;Norikazu Katayama;Kazumasa Yokoyama;Takeshi Inoue;Hiroko Izumi‐Nakaseko;S. Kakuta;K. Sudo;Y. Iwakura;H. Umemori;Takafumi Inoue;N. Murphy;K. Hashimoto;M. Kano;T. Manabe;Tadashi Yamamoto
S. Taniguchi;A. Tanimura;Y. Kiyama;T. Tezuka;A. M. Watabe;Norikazu Katayama;Kazumasa Yokoyama;Takeshi Inoue;Hiroko Izumi‐Nakaseko;S. Kakuta;K. Sudo;Y. Iwakura;H. Umemori;Takafumi Inoue;N. Murphy;K. Hashimoto;M. Kano;T. Manabe;Tadashi Yamamoto
中科院分区:
其他
文献类型:
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作者:
S. Taniguchi;A. Tanimura;Y. Kiyama;T. Tezuka;A. M. Watabe;Norikazu Katayama;Kazumasa Yokoyama;Takeshi Inoue;Hiroko Izumi‐Nakaseko;S. Kakuta;K. Sudo;Y. Iwakura;H. Umemori;Takafumi Inoue;N. Murphy;K. Hashimoto;M. Kano;T. Manabe;Tadashi Yamamoto

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你的手稿现在终于被三位裁判看到了,他们对作者的评论如下所示。正如你将看到的,评审员对这项研究相当积极,如果你能进一步加强手稿,他们会支持在EMBO期刊上发表文章。提出的一个主要问题是,YF/YF小鼠的行为特征需要按照建议的路线进行扩展。其次,评审员认为,对转基因细胞进行的一些功能实验应该用来自YF/YF和WT小鼠的神经元进行。因此,如果你能以适当的方式处理这些问题和裁判提出的其他观点,我们将乐于考虑修改后的手稿。
Your manuscript has now finally been seen by three referees whose comments to the authors are shown below. As you will see the referees are quite positive about the study and would support publication in The EMBO Journal if you could strengthen the manuscript further. One of the major issues raised is that the behavioural characterisation of the YF/YF mice needs to be expanded along the lines suggested. Second, the referees feel that some of the functional experiments that were performed with transfected cells should be performed with neurons from the YF/YF and WT mice. We should thus be happy to consider a revised manuscript if you can address these issues and the other points raised by the referees in an adequate manner.