Hematopoietic stem cell transplantation for MDS.
Hematopoietic stem cell transplantation for MDS.
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DOI:
10.1016/j.hoc.2010.02.003
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发表时间:
2010-04
期刊:
影响因子:
--
通讯作者:
Deeg HJ
中科院分区:
文献类型:
--
作者:
Bartenstein M;Deeg HJ
Hematopoietic stem cell transplantation (HSCT) offers potentially curative therapy for patients with myelodysplastic syndromes (MDS). However, as the majority of patients with MDS are in the 7th or 8th decade of life, conventional transplant regimens have been used only infrequently, and only with the development of reduced-intensity conditioning has transplantation been applied more broadly to older patients. Dependent upon disease status at the time of transplantation, 30–70% of patients can be expected to be cured of their disease and survive long-term. However, post-transplant relapse and graft-versus-host disease (GVHD) remain problems and further instigations are needed.
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