A fast dose calculation method based on table lookup for IMRT optimization.
A fast dose calculation method based on table lookup for IMRT optimization.
复制标题
DOI：
10.1088/0031-9155/48/12/401
复制
发表时间：
2003-06
影响因子：
3.5
通讯作者：
Qiuwen Wu;D. Djajaputra;M. Lauterbach;Yan Wu;R. Mohan
中科院分区：
文献类型：
--
作者：
Qiuwen Wu;D. Djajaputra;M. Lauterbach;Yan Wu;R. Mohan
本文描述了一种快速剂量计算方法，可用于加速调强放射治疗(IMRT)的优化过程。调强放射治疗中的大多数迭代优化算法需要大量的剂量计算才能达到收敛，因此使用更快的剂量计算方法可以大大减少调强放疗计划所需的总时间。本笔记中描述的方法依赖于精确的剂量计算引擎，该引擎用于计算治疗计划中使用的每一束的近似剂量核。一旦计算并保存了内核，就可以通过查找该内核来快速完成后续的剂量计算。在这种方法中，由于内核的近似性质而导致的不准确性可以通过执行预定的内核更新来减少。这种快速剂量计算方法的执行速度可以比典型的叠加/卷积方法快两个数量级以上，因此适用于速度非常关键的应用，例如，在需要模拟退火法优化算法的调强放射治疗优化中或在实际的调强放射治疗束角优化系统中。
This note describes a fast dose calculation method that can be used to speed up the optimization process in intensity-modulated radiotherapy (IMRT). Most iterative optimization algorithms in IMRT require a large number of dose calculations to achieve convergence and therefore the total amount of time needed for the IMRT planning can be substantially reduced by using a faster dose calculation method. The method that is described in this note relies on an accurate dose calculation engine that is used to calculate an approximate dose kernel for each beam used in the treatment plan. Once the kernel is computed and saved, subsequent dose calculations can be done rapidly by looking up this kernel. Inaccuracies due to the approximate nature of the kernel in this method can be reduced by performing scheduled kernel updates. This fast dose calculation method can be performed more than two orders of magnitude faster than the typical superposition/convolution methods and therefore is suitable for applications in which speed is critical, e.g., in an IMRT optimization that requires a simulated annealing optimization algorithm or in a practical IMRT beam-angle optimization system.