THE DYNAMIC CLAMP - ARTIFICIAL CONDUCTANCES IN BIOLOGICAL NEURONS
THE DYNAMIC CLAMP - ARTIFICIAL CONDUCTANCES IN BIOLOGICAL NEURONS
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DOI：
10.1016/0166-2236(93)90004-6
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发表时间：
1993-10-01
影响因子：
15.9
通讯作者：
MARDER, E
中科院分区：
文献类型：
--
作者：
SHARP, AA;ONEIL, MB;MARDER, E
动态钳位是一种利用计算机模拟将电导引入生物神经元的新方法。这种方法可以用来研究各种电导在塑造单个神经元或网络内神经元的活动中的作用。动态箝位也可以用来从先前未连接的神经元形成电路。这种方法使计算机模拟成为一种交互式的实验工具，并将在许多对突触强度和内在特性在神经元和网络动力学中的作用感兴趣的应用中发挥作用
The dynamic clamp is a novel method that uses computer simulation to introduce conductances into biological neurons. This method can be used to study the role of various conductances in shaping the activity of single neurons, or neurons within networks. The dynamic clamp can also be used to form circuits from previously unconnected neurons. This approach makes computer simulation in interactive experimental tool, and will be useful in many applications where the role of synaptic strengths and intrinsic properties in neuronal and network dynamics is of interest