Pediatric Infectious Diseases Related to Transplantation: Insights From Japan
Pediatric Infectious Diseases Related to Transplantation: Insights From Japan
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与移植相关的儿科传染病：日本的见解
DOI：
10.1097/inf.0000000000003731
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发表时间：
2022
影响因子：
3.6
通讯作者：
Saitoh Akihiko
中科院分区：
文献类型：
--
作者：
Yamada Masaki;Shoji Kensuke;Miyairi Isao;Kasahara Mureo;Saitoh Akihiko
移植后的感染性疾病占显著的发病率和死亡率在接受移植的儿童;因此，儿科移植感染性疾病（TID）专家的重要性已被公认。尽管移植医学继续取得巨大进步，但儿科特异性数据和证据有限。在日本，大多数TID没有由传染病专家管理，因为直到最近日本才将儿科传染病视为一个单独的亚专科。然而，在过去的十年中，在日本出现了儿科TID的新动向;一些在日本境外接受培训的儿科传染病专家在一些学术和儿科机构的儿科TID管理中发挥了重要作用。在这篇综述文章中，我们介绍了与儿科造血细胞和实体器官移植相关的感染性并发症的现状，突出了日本儿科TID领域目前可用的本地证据、常见做法和问题。
Infectious diseases after transplantation account for significant morbidity and mortality in children undergoing transplantation; the importance of pediatric transplant infectious disease (TID) specialists has therefore been recognized. Although tremendous advancement continues in transplantation medicine, pediatric-specific data and evidence are limited. In Japan, the majority of TIDs had not been managed by infectious disease specialists because pediatric infectious diseases have not been recognized as a solo subspecialty until recently in Japan. However, in the last decade, there was a new movement for pediatric TID in Japan; some pediatric infectious disease specialists trained outside Japan have been playing an important role in managing pediatric TID in a few academic and pediatric institutions. In this review article, we introduce the current status of infectious complications related to pediatric hematopoietic cell and solid organ transplantation, highlighting currently available local evidence, common practice and issues in the field of pediatric TID in Japan.