Large-field-of-view, modular, stabilized, adaptive-optics-based scanning laser ophthalmoscope

Large-field-of-view, modular, stabilized, adaptive-optics-based scanning laser ophthalmoscope
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DOI:
10.1364/josaa.24.001313
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发表时间:
2007-05-01
影响因子:
1.9
通讯作者:
Hammer, Daniel X.
Hammer, Daniel X.
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Burns, Stephen A.;Tumbar, Remy;Hammer, Daniel X.

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我们描述了一种自适应光学视网膜成像仪的设计和性能,该成像仪被优化用于眼动的动态校正。该系统包括一个视网膜跟踪器和稳定器,一个宽视场行扫描激光眼底镜(SLO),以及一个基于高分辨率微机电系统的自适应光学SLO。该检测系统结合了共焦孔的选择和定位,允许测量从双程视网膜点扩展函数(PSF)的不同部分产生的图像。系统性能非常好。自适应光学系统将小共焦光圈的亮度和对比度提高了2倍以上,并降低了光圈移位后获得的图像的亮度,证实了自适应光学系统改善PSF的能力。90%的时间视网膜图像稳定在18微米以内。稳定性足以使互相关技术自动对齐图像。(C)2007年美国光学学会。
We describe the design and performance of an adaptive optics retinal imager that is optimized for use during dynamic correction for eye movements. The system incorporates a retinal tracker and stabilizer, a wide-field line scan scanning laser ophthalmoscope (SLO), and a high-resolution microelectromechanical-systems-based adaptive optics SLO. The detection system incorporates selection and positioning of confocal apertures, allowing measurement of images arising from different portions of the double pass retinal point-spread function (psf). System performance was excellent. The adaptive optics increased the brightness and contrast for small confocal apertures by more than 2x and decreased the brightness of images obtained with displaced apertures, confirming the ability of the adaptive optics system to improve the psf. The retinal image was stabilized to within 18 mu m 90% of the time. Stabilization was sufficient for cross-correlation techniques to automatically align the images. (c) 2007 Optical Society of America.