Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: A randomized placebo-controlled trial
Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: A randomized placebo-controlled trial
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DOI：
10.1097/01.pcc.0000282176.41134.e6
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发表时间：
2007-09-01
影响因子：
4.1
通讯作者：
Kocis, Keith C.
中科院分区：
文献类型：
--
作者：
Honeycutt, Travis C. B.;El Khashab, Mohamed;Kocis, Keith C.
目的：评估益生菌在降低儿科重症监护中院内感染率方面的功效。设计：随机、双盲、安慰剂对照试验。地点：大学附属儿童医院的 16 个床位的儿科重症监护病房。患者：2004 年 4 月至 2004 年 12 月期间入组了 61 名儿科患者。 每日一次。如果患者有以下情况则被排除：肠穿孔的证据/怀疑、机械性胃肠道梗阻的证据/怀疑、中性粒细胞绝对计数
Objective: To evaluate the efficacy of probiotics in reducing the rates of nosocomial infection in pediatric intensive care.Design: Randomized, double-blind, placebo-controlled trial.Setting: A 16-bed pediatric intensive care unit in a university-affiliated children's hospital.Patients: Sixty-one pediatric patients were enrolled from April 2004 until December 2004. Screening of all patients admitted occurred on a daily basis. Patients were excluded if they had the following: evidence/suspicion of intestinal perforation, evidence/ suspicion of mechanical gastrointestinal obstruction, absolute neutrophil count