Extraction of pharmaceutical composition from Chinese eaglewood and its therapeutic efficacy

Extraction of pharmaceutical composition from Chinese eaglewood and its therapeutic efficacy
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沉香药物组合物的提取及其治疗功效

DOI:
10.15376/biores.14.2.3780-3794
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发表时间:
2019
期刊:
影响因子:
1.5
通讯作者:
Shen Huajie
Shen Huajie
中科院分区:
材料科学4区
文献类型:
--
作者:
P. Zhihong;Jian Qiu;Haishan He;Qingde Li;Shen Huajie

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关于沉香提取物对中风诱发的神经与神经功能障碍引起的运动功能障碍之间关系的影响鲜有报道。本研究成功地从白沉香中诱导出脂质,并分析了提取原因。通过对照临床实验研究沉香提取物作为药物治疗对中风患者神经和运动功能恢复的影响。使用脑电图(EEG)测试、Fugl-Meyer 上肢量表和 Fugl-Meyer 下肢量表进一步分析了此类影响。研究结果表明,使用沉香提取物通过代偿作用促进中风患者的神经功能恢复,进一步改善患者的运动功能恢复。因此,从Fugl-Meyer上肢和下肢量表的结果来看,中风患者的运动功能在临床实验过程中逐渐恢复,这表明神经功能已经恢复。 RNA提取结果显示RNA纯度高,不含蛋白质,并且使用混合诱导剂可以获得干扰物质。本研究论证了沉香提取物应用的可行性及其治疗功效。
There are few reports on the effect of Chinese eaglewood extractions on the relationship between a stroke-induced nerve and the motor dysfunction caused by the nerve dysfunction. In this study, lipids were successfully induced from white eaglewood, and the cause of extraction were analyzed. Controlled clinical experiments were conducted to study the effects of Chinese eaglewood extracts as a drug therapy on the recovery of nerve and motor function of stroke patients. Such effects were further analyzed using the electroencephalograms (EEGs) test, the Fugl-Meyer upper extremity scale, and the Fugl-Meyer lower extremity scale. The results of the study showed that the nerve function recovery of stroke patients through compensatory effects was promoted by using Chinese eaglewood extracts, and the motor function recovery of patients was further improved. Thus, from the results of the Fugl-Meyer upper extremity and lower extremity scales, the motor functions of the stroke patients were gradually recovered during the clinical experiments, which indicated nerve function recovery. The RNA extraction results showed high RNA purity without the presence of proteins and that interfering substances can be obtained by using the mixed inducer agent. This study demonstrated the feasibility for the application of Chinese eaglewood extracts and its therapeutic efficacy.
DOI: 10.1161/01.str.0000189658.51972.34
发表时间: 2005-12-01
期刊: STROKE
影响因子: 8.3
作者:
Takeuchi, N;Chuma, T;Ikoma, K
通讯作者: Ikoma, K