Thyroxine-evoked decrease of jejunal lactase activity in adult rats.
Thyroxine-evoked decrease of jejunal lactase activity in adult rats.
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甲状腺素引起成年大鼠空肠乳糖酶活性降低。
DOI：
10.1016/s0016-5085(19)32232-2
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发表时间：
1977
期刊：
影响因子：
29.4
通讯作者：
O. Koldovský
中科院分区：
文献类型：
--
作者：
P. Celano;J. Jumawan;O. Koldovský
成年雄性大鼠每日给予L-甲状腺素（20 μg或20 μg/100 g体重），2、3、4和10天后空肠乳糖酶活性降低35%。注射D-甲状腺素（200 μg/100 g体重/天）4天后，乳糖酶活性也出现了类似的下降。蔗糖酶活性不受影响，但每日注射L-甲状腺素（200 μg/100 g体重）10天后增加30%。酸性G-半乳糖苷酶活性不受D-或L-甲状腺素的影响。
Daily administration of L-thyroxine (20 μg or 20 μg/100 g body weight) to adult male rats decreased jejunal lactase activity by 35% after 2-, 3-, 4- and 10 days. Four days of injections of D-thyroxine (200 μg/100 g body weight/day) produced a similar decrease of lactase activity. Sucrase activity was uninfluenced except for a 30% increase after daily injections of L-thyroxine (200 μg/100 g body weight) for 10 days. Acid g-galactosidase activity was unaffected by either D- or L-thyroxine.