The red cell membrane skeleton: recent progress.

The red cell membrane skeleton: recent progress.
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红细胞膜骨架:最新进展。

DOI:
10.1182/blood.v61.1.1.1
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发表时间:
1983
期刊:
影响因子:
20.3
通讯作者:
V. Marchesi
V. Marchesi
中科院分区:
医学1区
文献类型:
--
作者:
V. Marchesi

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人们普遍认为,红细胞膜的脂质双层由复杂的蛋白质分子基础结构支撑,赋予其粘弹性。提供这种功能的蛋白质通常被称为“膜骨架”。这种膜骨架被认为与所谓的“细胞骨架”不同,“细胞骨架”是细胞生物学家用来描述将细胞不同部分相互连接以及与膜连接的复杂管子和纤维阵列的术语。在大多数细胞中,细胞骨架显然与细胞形状的维持有关,并且可能还在细胞运动中发挥作用。据推测,在同时具有细胞骨架和膜骨架的细胞中,两者之间存在连接,但无核红细胞仅依赖膜骨架来赋予形状和稳定性。也许正是由于这个原因,红细胞的膜骨架是精心设计的多蛋白复合物。
I T IS WIDELY believed that the lipid bilayer of the erythrocyte membrane is supported by an elaborate infrastructure of protein molecules that give it viscoelastic properties. The proteins that provide this function are popularly referred to as the “membrane skeleton.” This membrane skeleton is considered to be distinct from the so-called “cytoskeleton,” a term used by cell biologists to describe the complex array of tubes and fibers that connect different parts of cells to each other and to the membrane. In most cells the cytoskeleton is clearly involved with the maintenance of cell shape and probably also plays a role in cell movement. It is assumed that connections exist between the cytoskeleton and the membrane skeleton in cells that have both, but nonnucleated red cells rely solely on the membrane skeleton to confer shape and stability. Perhaps for this reason, membrane skeletons of red cells are elaborately engineered, multiprotein complexes.
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DOI: 10.1002/jsscb.380170308
发表时间: 1981
期刊: Journal of supramolecular structure and cellular biochemistry
影响因子: --
作者:
Morrow,JS;HaighJr,WB;Marchesi,VT
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发表时间: 1980
影响因子: 11.1
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DOI: --
发表时间: 1982
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DOI: --
发表时间: 1982
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DOI: --
发表时间: 1980
期刊: The Journal of biological chemistry
影响因子: --
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