DIFFERENCES IN HUMAN EVOKED-POTENTIALS RELATED TO OLFACTORY OR TRIGEMINAL CHEMOSENSORY ACTIVATION
DIFFERENCES IN HUMAN EVOKED-POTENTIALS RELATED TO OLFACTORY OR TRIGEMINAL CHEMOSENSORY ACTIVATION
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DOI：
10.1016/0168-5597(92)90070-r
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发表时间：
1992-01-01
期刊：
影响因子：
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通讯作者：
KOBAL, G
中科院分区：
文献类型：
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作者：
HUMMEL, T;KOBAL, G
本研究的目的是确定化学感觉诱发电位（csep）在不同气味物质刺激下的地形分布是否存在差异。研究中使用的主要刺激嗅觉神经的气味剂是香兰素和乙醛；另外刺激三叉神经的是二氧化硫和氨。12名受试者参与了这项研究。受试者分别估计气味的强度和刺激引起的疼痛/刺痛感，并用他们自己的话描述气味的性质。从7个位置记录csep。在“嗅觉”物质刺激后，最大的CSEP振幅记录在顶叶到中枢部位，而在“三叉”物质刺激后，最大的CSEP振幅记录在顶点。用氨和二氧化硫刺激后，对侧鼻孔的振幅最大。相比之下，用香草醛或乙醛刺激后，在两个半球之间观察到的CSEP振幅几乎没有差异。因此，CSEP振幅的地形分布可以提供有关嗅觉或三叉神经系统被气味刺激激活的信息。
The aim of the present study was to determine, whether there are differences in the topographical distribution of chemosensory evoked potentials (CSEPs) due to stimulation with different odorous substances. The odorants used in the study which mainly excited the olfactory nerve were vanillin and acetaldehyde; those which additionally excited the trigeminal nerve were sulphur dioxide and ammonia. Twelve subjects participated in the study. The subjects separately estimated the intensity of the odorous and of the painful/pricking sensation caused by the stimuli, and described the odorous qualities in their own words. CSEPs were recorded from 7 positions.After stimulation with "olfactory" substances maximum CSEP amplitudes were recorded at parieto-central sites, and after stimulation with "trigeminal" substances maximum amplitudes were obtained at the vertex. Following stimulation with ammonia and sulphur dioxide amplitudes were largest contralateral to the stimulated nostril. In contrast, little difference in CSEP amplitudes was observed between hemispheres after stimulation with vanillin or acetaldehyde.Thus, the topographical distribution of CSEP amplitudes may provide information with regard to the sensory system (olfactory or trigeminal) activated by the presentation of an odorous stimulus.