Cohort Profile: Cohort of Norway (CONOR)
Cohort Profile: Cohort of Norway (CONOR)
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DOI：
10.1093/ije/dym217
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发表时间：
2008-06-01
影响因子：
7.7
通讯作者：
Aamodt, Geir
中科院分区：
文献类型：
--
作者：
Naess, Oyvind;Sogaard, Anne Johanne;Aamodt, Geir
自20世纪70年代初以来，挪威进行了许多基于人群的大规模心血管调查。这些调查是由国家健康检查局与大学和地方卫生当局合作进行的。所有调查都包括一组共同的问题、标准化的人体测量和血压测量以及在Ullevål医院实验室分析血脂的非空腹血液样本。这些调查为开展大规模人口调查提供了大量经验，因此是挪威队列的重要背景。1980年代后期，挪威研究理事会设立了一个流行病学方案。这也激发了建立一个既包括核心调查数据又包括储存的血液样本的队列的想法。20世纪90年代初，所有大学、国家健康筛查服务、国家公共卫生研究所和癌症登记处讨论了建立一个全国代表性队列的可能性。1储存血样供今后分析的问题引起了一些关注，议会对此进行了讨论。1994年，卫生部任命了CONOR合作指导委员会。1994- 1995年，进行了第四轮特罗姆斯研究，并成为第一次为CONOR提供数据和血液样本的调查。1994-2003年期间，在其他县市进行的一些健康调查也为该网络提供了类似的数据。到目前为止，已有10项不同的调查为CONOR提供了数据和血液样本（图1）。2002年，挪威国家康复委员会的行政责任交给了挪威公共卫生研究所。CONOR合作目前是NIPH与卑尔根大学、奥斯陆大学、特罗姆瑟大学和特隆赫姆大学之间的研究合作。
A number of large population-based cardiovascular surveys have been conducted in Norway since the beginning of the 1970s. The surveys were carried out by the National Health Screening Service in cooperation with the universities and local health authorities. All surveys comprised a common set of questions, standardized anthropometric and blood pressure measurements and non-fasting blood samples that were analysed for serum lipids at the Ullevål Hospital Laboratory. These surveys provided considerable experience in conducting large-scale population-based surveys, thus an important background for the Cohort of Norway (CONOR). In the late 1980s the Research Council of Norway established a programme in epidemiology. This also gave stimulus to the idea of establishing a cohort including both core survey data and stored blood samples. In the early 1990s, all universities, the National Health Screening Service, The National Institute of Public Health and the Cancer Registry discussed the possibility of a national representative cohort. 1 The issue of storing blood samples for future analyses raised some concern and it was discussed in the parliament. In 1994, the Ministry of Health appointed the Steering Committee for the CONOR collaboration. In 1994–95, the fourth round of the Tromsø Study was conducted, and became the first survey to provide data and blood samples for CONOR. During the years 1994–2003, a number of health surveys that were carried out in other counties and cities also provided similar data for the network. So far, 10 different surveys have provided data and blood samples for CONOR (Figure 1). The administrative responsibility for CONOR was given to the Norwegian Institute of Public Health (NIPH) in 2002. The CONOR collaboration is currently a research collaboration between the NIPH and the Universities of Bergen, Oslo, Tromsø and Trondheim.