Mitochondrial-type hsp70 genes of the amitochondriate protists, Giardia intestinalis, Entamoeba histolytica and two microsporidians
Mitochondrial-type hsp70 genes of the amitochondriate protists, Giardia intestinalis, Entamoeba histolytica and two microsporidians
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DOI：
10.1016/s1383-5769(01)00093-9
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发表时间：
2002-03-01
影响因子：
1.9
通讯作者：
Hashimoto, T
中科院分区：
文献类型：
--
作者：
Arisue, N;Sáchez, LB;Hashimoto, T
从无线粒体原生生物贾第鞭毛虫、溶组织内阿米巴和两种微孢子虫脑孢子虫Hellem和Glugea plecoglossi中分离并测序了编码假定的肠型热休克蛋白70（mit-hsp 70）的基因。对推导的mit-hsp 70序列进行序列比对和系统发育分析。这四种无线粒体原生生物的mit-hsp 70序列与其他哺乳动物真核生物的mit-hsp 70序列不同。然而，所有这些序列都清楚地位于一个真核线粒体进化枝的树，包括各种类型的热休克蛋白70序列，支持新兴的概念，没有这些amitochondriate谱系是连续的amitochodrial，但失去了他们的线粒体二次在他们的进化过去。(C)2002爱思唯尔科学爱尔兰有限公司保留所有权利。
Genes encoding putative mitochondrial-type heat shock protein 70 (mit-hsp70) were isolated and sequenced from amitochondriate protists, Giardia intestinalis, Entamoeba histolytica, and two microsporidians, Encephalitozoon hellem and Glugea plecoglossi. The deduced mit-hsp70 sequences were analyzed by sequence alignments and phylogenetic reconstructions. The mit-hsp70 sequence of these four amitochondriate protists were divergent from other mit-hsp70 sequences of mitochondriate eukaryotes. However, all of these sequences were clearly located within a eukaryotic mitochondrial clade in the tree including various type hsp70 sequences, supporting the emerging notion that none of these amitochondriate lineages are primitively amitochodrial, but lost their mitochondria secondarily in their evolutionary past. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.