The neural basis of maternal responsiveness to infants: an fMRI study
The neural basis of maternal responsiveness to infants: an fMRI study
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DOI：
10.1097/01.wnr.0000137078.64128.6a
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发表时间：
2004-08-06
期刊：
影响因子：
1.7
通讯作者：
Appleby, L
中科院分区：
文献类型：
--
作者：
Ranote, S;Elliott, R;Appleby, L
使用功能磁共振成像，我们检查了母亲反应性的神经关联。10位健康的母亲观看了交替的视频块：(I)40个自己婴儿的S；(Ii)20个中性视频的S；(Iii)40个未知婴儿的S和(Iv)20个中性视频的S，重复4次。双侧视加工区(BA38)、左侧杏仁核和视皮层(BA19)、双侧眶前叶皮质(BA10、47)和内侧前额叶皮质(BA8)分别出现双侧视加工区(BA38)、左侧杏仁核和视皮层(BA19)、不明婴儿双侧眶前叶皮质(BA10、47)和内侧前额叶皮质(BA8)的双侧视加工区(BA38)、左侧杏仁核(BA19)和双侧眶前叶皮质(BA8)的双侧视加工区(BA38)、左侧杏仁核(BA19)、双侧眶前叶皮质(BA10、47)和内侧前额叶皮质(BA8)。这些发现表明，杏仁核和颞极可能是调节母亲对婴儿反应的关键部位，并重申了它们在面孔、情绪处理和社交行为中的重要性。
Using fMRI, we examined the neural correlates of maternal responsiveness. Ten healthy mothers viewed alternating blocks of video: (i) 40 s of their own infant; (ii) 20 s of a neutral video; (iii) 40 s of an unknown infant and (iv) 20 s of neutral video, repeated 4 times. Predominant BOLD signal change to the contrast of infants minus neutral stimulus occurred in bilateral visual processing regions BA minus neutral stimulus occurred in bilateral visual processing regions (BA 38), left amygdala and visual cortex (BA 19), and to the unknown infant minus own infant contrast in bilateral orbitofrontal cortex (BA 10,47) and medial prefrontal cortex (BA 8). These findings suggest that amygdala and temporal pole may be key sites in mediating a mother's response to her infant and reaffirms their importance in face emotion processing and social behaviour.