Discovery of two potential DAZL gene markers for sperm quality in boars by population association studies
Discovery of two potential DAZL gene markers for sperm quality in boars by population association studies
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通过群体关联研究发现两种潜在的公猪精子质量 DAZL 基因标记
DOI：
10.1016/j.anireprosci.2013.10.002
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发表时间：
2013-12-01
影响因子：
2.2
通讯作者：
Li, Fenge
中科院分区：
文献类型：
--
作者：
Ma, Changping;Li, Jialian;Li, Fenge
AZoospermia Like （DAZL）基因是DAZ （AZoospermia Deleted in AZoospermia）基因家族的一员，该基因对多种动物生殖细胞的成功发育至关重要。在之前的研究中，我们发现了两个与母猪产仔数性状相关的snp （DAZL C .570+385 A>G, DAZL C .735+150 C>A）。基于DAZL基因在精子发生过程中对生殖细胞形成的作用，我们选择了DAZL基因作为猪精子质量性状的候选基因，并分析了这两个snp与杜洛克（n= 185）、大白（n=87）和长白（n=49）猪群体精子质量性状的关系。结果表明：DAZL c.570+385 AG型公猪的运动力（MOT）显著高于GG型公猪(P
The Deleted in AZoospermia Like (DAZL) gene is a member of the DAZ (deleted in azoospermia) gene family which are critical for successful germ cell development in diverse animals. In previous research, we discovered two SNPs (DAZL c.570+385 A>G, DAZL c.735+150 C>A) associated with litter size traits in sows. Here we selected DAZL gene as a candidate gene for boar sperm quality traits based on its function on the formation of germ cells during spermatogenesis, and then analyzed the associations of the two SNPs with sperm quality traits in Duroc (n =185), Large White (n=87) and Landrace (n=49) pig populations. The results showed DAZL c.570+385 AG boars had significantly higher motility (MOT) than GG boars (P