The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprinting
The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprinting
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DOI：
10.1038/ng1495
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发表时间：
2005-01-01
期刊：
影响因子：
30.8
通讯作者：
Grossniklaus, U
中科院分区：
文献类型：
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作者：
Köhler, C;Page, DR;Grossniklaus, U
母本表达的拟南芥Polycomb组蛋白MEDEA（MEA）控制MADS盒基因PHERES 1（PHE1）的表达。在这里，我们表明，PHE1主要是父系表达，但母系压抑，这种母系压抑的PHE1打破种子缺乏母亲MEA活动。由于Polycomb组蛋白也控制哺乳动物的亲本印记，因此独立招募相似的蛋白质机器进行基因印记是趋同进化的一个显著例子。
The maternally expressed Arabidopsis thaliana Polycomb group protein MEDEA (MEA) controls expression of the MADS-box gene PHERES1 (PHE1). Here, we show that PHE1 is mainly paternally expressed but maternally repressed and that this maternal repression of PHE1 breaks down in seeds lacking maternal MEA activity. Because Polycomb group proteins control parental imprinting in mammals as well, the independent recruitment of similar protein machineries for the imprinting of genes is a notable example of convergent evolution.