A case report of a patient with rheumatoid arthritis complicated with Mycobacterium avium during tocilizumab treatment
A case report of a patient with rheumatoid arthritis complicated with Mycobacterium avium during tocilizumab treatment
复制标题
DOI：
10.1007/s10165-011-0448-1
复制
发表时间：
2011-12-01
影响因子：
2.2
通讯作者：
Maeda, Keiji
中科院分区：
文献类型：
--
作者：
Nakahara, Hideko;Kamide, Yosuke;Maeda, Keiji
1例女性类风湿性关节炎(RA)患者在托奇珠单抗治疗过程中感染禽型分枝杆菌。Tocilizumab停用，她接受了推荐的化疗，导致禽型支原体好转。Tocilizumab再次治疗没有加重禽类支原体感染，在停止推荐治疗一年多后，放射学异常有所改善。如果需要生物学治疗，tocilizumab可能是难治性类风湿性关节炎患者的候选药物之一。
A female patient with rheumatoid arthritis (RA) suffered from Mycobacterium avium (M. avium) infection during tocilizumab treatment. Tocilizumab was discontinued and she was treated with a recommended chemotherapy, resulting in improvement of M. avium. Tocilizumab retreatment did not aggravate M. avium infection, and radiographic abnormalities improved over 1 year after cessation of the recommended therapy. Tocilizumab may be one candidate for intractable RA patients with M. avium if any biologic is required.