The neuropsychological profile associated with variant Creutzfeldt-Jakob disease
The neuropsychological profile associated with variant Creutzfeldt-Jakob disease
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DOI：
10.1093/brain/awg279
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发表时间：
2003-12-01
期刊：
影响因子：
14.5
通讯作者：
Will, RG
中科院分区：
文献类型：
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作者：
Kapur, N;Abbott, P;Will, RG
我们报告与变异型克雅氏病（vCJD）相关的神经心理学特征。对24例vCJD患者的神经心理学报告进行了回顾性研究。虽然神经心理学特征存在一些差异，但总体模式是皮质和皮质下痴呆的结合，在记忆、执行功能、注意力速度和视知觉推理测试中，表现受损尤其突出。在16例有韦氏成人智力量表修订版智商（IQ）评分的病例中，这一特征部分反映在无一例外地表现为低智商（
We report the neuropsychological profile associated with variant Creutzfeldt-Jakob disease (vCJD). A retrospective study was carried out of data from neuropsychological reports prepared on 24 patients with vCJD. While there was some variability in neuropsychological profiles, the overall pattern was one of a combined cortical and subcortical dementia, with impaired performance being particularly prominent on tests of memory, executive function, speed of attention, and visuoperceptual reasoning. Across 16 cases where Wechsler Adult Intelligence Scale-Revised intelligence quotient (IQ) scores were available, this profile was in part reflected by an invariably low performance IQ (