Development of a Piezoelectric Actuated Tactile Stimulation Device for Population Receptive Field Mapping in Human Somatosensory Cortex With <scp>fMRI</scp>
Development of a Piezoelectric Actuated Tactile Stimulation Device for Population Receptive Field Mapping in Human Somatosensory Cortex With <scp>fMRI</scp>
复制标题
开发压电驱动触觉刺激装置，利用 <scp>fMRI</scp> 进行人类体感皮层群体感受野绘图
DOI：
10.1002/jmri.28173
复制
发表时间：
2022
影响因子：
4.4
通讯作者：
Zhang Jian
中科院分区：
文献类型：
--
作者：
Wu Jinglong;Wang Chenyu;Wang Luyao;Wang Yutong;Yang Jiajia;Yan Tianyi;Suo Dingjie;Wang Li;Liu Xin;Zhang Jian
研究背景多道触觉刺激装置是在功能磁共振成像(FMRI)过程中需要研究人类手指初级体感皮层群体感受野的特征。目的基于贝叶斯体感刺激模型准确描述右侧体感表征。研究类型展望人口一个水模和6名健康受试者(4名男性，平均23.8 岁)。场强/序列T1加权磁化准备快速梯度回波，T2*加权回波平面成像在3℃时。评价：压电驱动触觉刺激器由执行单元和控制单元组成。利用激光位移传感器对器件的输出性能进行了测量。通过体模实验测量了该装置对图像信噪比的影响。在顺指和横指范式下，对右手的激活表征排列顺序、相对体积和感受野大小进行评估。进行配对抽样测试，以测试所有数字配对的PRF特性。结果压电式触觉刺激器提供的触觉刺激在较宽的振动频率范围内(0~30 Hz)有稳定的位移(2.64 mm)。该设备的输出延迟为1微秒。该设备不影响图像的信噪比(没有设备：SNR=138.24 ± 7.87，时间信噪比[TSNR] =约440.03 ± 52.08.该装置的信噪比为138.06 ± 8.44，信噪比为438.52 ± 为56.38。在两个实验中，右手手指的表征呈现出相同的排列顺序(d1-d5沿中央沟排列)。而D3的相对体积与S1相比，差异有统计学意义(P=0.003)。在4个亚区中，D3的相对体积在1区有显著差异(P=0.0.047)。结论通过实验验证，该刺激物可以在PRF作图的探索中发挥作用
BackgroundMultichannel tactile stimulation devices is need to investigate human finger population receptive field (pRF) characteristics in the primary somatosensory cortex during functional magnetic resonance imaging (fMRI).PurposeTo accurately characterize right‐hand somatosensory representation based on the Bayesian pRF model.Study TypeProspective.PopulationA water phantom and six healthy participants (four males, mean 23.8 years old).Field Strength/SequenceT1‐weighted magnetization‐prepared rapid gradient‐echo, T2*‐weighted echo planar imaging at 3 T.AssessmentThe piezoelectric actuated tactile stimulation device consisted of execution unit and control unit. The output performance of the device was measured by a laser displacement sensor. The effect of the device on images' signal‐to‐noise ratio (SNR) was measured by phantom experiments. The activation representation arrangement order, relative volumes, and receptive field size of the right hand were assessed during the along‐digits and cross‐digits paradigms.Statistical TestsThe normality of the data was tested by the Shapiro–Wilk method. A paired‐samplettest was performed to test pRF characteristics for all digit pairings. The significance level was set toP= 0.05 (false discovery rate [FDR] correct).ResultsPercussive stimulation provided by the piezoelectric actuated tactile stimulator had a stable displacement (2.64 mm) over a wide range of vibration frequencies (0–30 Hz). The output delay of the device was 1 millisecond. The device did not affect the image's SNR (without the device: SNR = 138.24 ± 7.87, temporal SNR [TSNR] = 440.03 ± 52.08. With the device: SNR = 138.06 ± 8.44, TSNR = 438.52 ± 56.38.PSNR= 0.88,PTSNR= 0.46). Representations of right‐hand fingers showed the same arrangement order in both experiments (D1–D5 arranged along the central sulcus). However, the relative volumes of D3 showed significant differences in S1 (P= 0.003). Among four subareas, the relative volumes of D3 were significantly different in area 1 (P= 0.047).Data ConclusionThis developed stimulator, through experimental verification, could play a role in pRF mapping exploration.Level of Evidence2Technical Efficacy Stage1