A convenient synthesis of N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deoxyribonucleoside and 1-methyl-2'-deoxypseudoisocytidine.
A convenient synthesis of N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deoxyribonucleoside and 1-methyl-2'-deoxypseudoisocytidine.
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N,N-二苄基-2,4-二氨基嘧啶-2-脱氧核糖核苷和1-甲基-2-脱氧假异胞苷的便捷合成。
DOI：
10.1080/15257770902946090
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Benner,StevenA
中科院分区：
文献类型：
--
作者：
Wellington,KevinW;Ooi,HuaChee;Benner,StevenA
报道了N，N′-dibenzyl-2，4-diaminopyrimidine-2′-deoxyribonucleoside和1-甲基-2‘-脱氧假异胞苷的Heck偶联合成方法。提供了使用Heck偶联来合成N，N′-dibenzyl-2，4-diaminopyrimidine-2′-deoxyribonucleoside的尝试的综述，表明根据所使用的特定杂环伙伴的不同，结果具有显著的多样性。
The syntheses ofN,N′-dibenzyl-2,4-diaminopyrimidine-2′-deoxyribonucleoside and 1-methyl-2′-deoxypseudoisocytidine via Heck coupling are described. A survey of the attempts to use the Heck coupling to synthesizeN,N′-dibenzyl-2,4-diaminopyrimidine-2′-deoxyribonucleoside is provided, indicating a remarkable diversity in outcome depending on the specific heterocyclic partner used.