Non-invasive prenatal testing (NIPT) and pregnant women's views on good motherhood: a qualitative study
Non-invasive prenatal testing (NIPT) and pregnant women's views on good motherhood: a qualitative study
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DOI：
10.1038/s41431-021-00945-3
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发表时间：
2021-08-17
影响因子：
5.2
通讯作者：
Timmermans, Danielle R. M.
中科院分区：
文献类型：
--
作者：
Garcia, Elisa;Henneman, Lidewij;Timmermans, Danielle R. M.
妇女对负责任母亲的看法影响参与产前筛查的决策。先前的研究表明，妊娠早期联合检测的概率性质以及随后侵入性诊断的潜在要求是女性将产前筛查排除在道德责任之外的合理理由。这些道德障碍现在可能与无创产前检测 (NIPT) 的引入不再相关，导致女性感到有道德义务使用 NIPT 筛查作为负责任母亲的一部分。这项定性研究探讨了 NIPT 对女性关于产前筛查与负责任母亲的意义的道德信念的影响。我们对 29 名孕妇进行了半结构化访谈，她们在荷兰全国性研究 (TRIDENT-2) 中接受了 NIPT 作为一级筛查测试。结果表明，尽管准确性有所提高，而且对检测到的疾病缺乏治疗，但胎儿健康固有的不确定性，再加上通过胎儿异常扫描获得有关可采取行动的异常信息的可能性，支持了妇女的观点，即 NIPT 不是负责任母亲的义务。接受 NIPT 被认为是一个自由决定，涉及到每个妇女成为孩子和家庭的好母亲所需的信息。当 NIPT 扩大到包括可治疗或可预防的病症时，女性的观点可能会改变。
Women's views on responsible motherhood influence decision-making regarding participation in prenatal screening. Previous studies showed that the probabilistic nature of the first-trimester combined test and the potential requirement for subsequent invasive diagnostics serve as legitimate reasons for women to exclude prenatal screening from their moral responsibilities. These moral barriers might now be less relevant with the introduction of the non-invasive prenatal test (NIPT) resulting in women feeling a moral duty to use NIPT screening as part of responsible motherhood. This qualitative study explores the impact of NIPT on women's moral beliefs about the meaning of prenatal screening in relation to responsible motherhood. We performed semi-structured interviews with 29 pregnant women who were offered NIPT as a first-tier screening test within a Dutch nationwide study (TRIDENT-2). Results show that the inherent uncertainty about the fetus's health despite improved accuracy and the lack of treatment for a detected disorder, combined with the possibility to obtain information about actionable anomalies through the fetal anomaly scan, support women's perspectives that NIPT is not an obligation of responsible motherhood. Acceptance of NIPT is considered to be a free decision related to the information each woman needs to be a good mother for her child and her family. Women's views may change when NIPT has expanded to include treatable or preventable conditions.