Childhood urine mercury excretion: dental amalgam and fish consumption as exposure factors
Childhood urine mercury excretion: dental amalgam and fish consumption as exposure factors
复制标题
DOI：
10.1016/j.envres.2003.07.004
复制
发表时间：
2004-03-01
影响因子：
8.3
通讯作者：
Rouah, F
中科院分区：
文献类型：
--
作者：
Levy, M;Schwartz, S;Rouah, F
作者调查了汞合金充填和食用鱼类对4-8岁儿童尿汞水平(UHG)的影响。通过对60名儿童的调查发现，银汞合金充填组儿童的超高血糖水平显著高于非银汞合金充填组(几何平均值分别为1.412和0.436，P=0.0001)。报告鱼肉摄入量较高的受试者的超高糖化血红蛋白也显著较高(P=0.004)。单变量分析提供证据表明，在有银汞合金咀嚼表面的儿童中，超高血糖水平与年龄小(P=0.009)、身高矮(P=0.024)和体重低(P=0.049)有关。我们还发现尿汞与年龄(-0.378)、身高(-0.418)和体重(-0.391)呈负相关。多元Logistic回归模型显示，即使在调整了高鱼类摄入量(OR=8.66)和身高(OR=11.36)之后，银汞合金填充物的存在也会导致儿童发生高UHG的几率增加(OR=47.18)。(C)2003 Elsevier Inc.保留所有权利。
The authors investigated the effect of amalgam fillings and fish consumption on urine mercury level (UHg), in children aged 4-8 years old inclusive. Using a sample of 60 children, we found that children with amalgam fillings had significantly higher UHg levels than children without amalgams (geometric mean = 1.412 mug Hg/g versus 0.436 mug Hg/g, respectively, P = 0.0001). Subjects with reported higher fish consumption also had significantly higher UHgs (P = 0.004). Univariate analyses provide evidence of an association between elevated UHg level and young age (P = 0.009), short height (P = 0.024), and low weight (P = 0.049) in children with amalgam chewing surfaces. We also found a negative correlation between urine mercury and age (-0.378), height (-0.418), and weight (-0.391). A multiple logistic regression model shows that the presence of amalgam fillings leads to increased odds of high UHg in children (OR = 47.18), even after adjusting for high fish consumption (OR = 8.66) and height (OR = 11.36). (C) 2003 Elsevier Inc. All rights reserved.