Axial heterogeneity of organic cation transport along the rabbit renal proximal tubule: studies with brush-border membrane vesicles.
Axial heterogeneity of organic cation transport along the rabbit renal proximal tubule: studies with brush-border membrane vesicles.
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沿兔肾近曲小管有机阳离子转运的轴向异质性：刷状缘膜囊泡的研究。
DOI：
10.1016/0005-2736(87)90102-7
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
C. Schäli
中科院分区：
文献类型：
--
作者：
C. Montrose‐Rafizadeh;F. Roch;C. Schäli
使用兔肾外皮质（富含S1和S2）和外髓质（富含S3）制备的刷状缘膜囊泡来评估近曲小管中四乙铵转运的轴向异质性。囊泡制剂具有相似的 K m 值，但 V max 值不同，表明四乙铵分泌的轴向异质性可能是由于刷状缘膜转运的差异所致。
Brush-border membrane vesicles prepared from rabbit kidney outer cortex (rich in S1 and S2) and outer medulla (rich in S3) were used to evaluate the axial heterogeneity of tetraethylammonium transport in the proximal tubule. The vesicle preparations had similar K m values but the V max values differed, suggesting that axial heterogeneity of tetraethylammonium secretion may be due to differences in transport across the brush-border membrane.