INDUCTION OF MUTATIONS BY γ-RAYS IN PREGONIAL GERM CELLS OF ZEBRAFISH EMBRYOS

INDUCTION OF MUTATIONS BY γ-RAYS IN PREGONIAL GERM CELLS OF ZEBRAFISH EMBRYOS
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斑马鱼胚胎孕前生殖细胞γ射线诱导突变

DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
G. Streisinger
G. Streisinger
中科院分区：
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文献类型：
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作者：
C. Walker;G. Streisinger

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在斑马鱼的裂解分裂期间，具有高频（约10（-5）r（-1））的伽玛射线诱导了特定的基因座（GOL-1）生殖系突变。当胚胎在16至10（3）个细胞阶段暴露时，突变克隆大小的范围从生殖细胞总数的3％到50％，平均约为10％。计算大约五个阶段性细胞在裂解期间存在。
Specific locus (gol-1) germ line mutations are induced by gamma-rays with high frequencies (about 10(-5) r( -1)) during cleavage divisions in zebrafish. Mutant clone sizes range from 3 to 50% of the total number of germ cells, with a mean of about 10%, when embryos are exposed between the 16 and 10(3) cell stages. About five pregonial cells are calculated to be present during the cleavage period.