Triphasic Continuous-Flow Oxidation System for Alcohols Utilizing Graft-Polymer-Supported TEMPO
Triphasic Continuous-Flow Oxidation System for Alcohols Utilizing Graft-Polymer-Supported TEMPO
复制标题
DOI：
10.1002/ajoc.201800125
复制
发表时间：
2018-06-01
影响因子：
2.7
通讯作者：
Takeda, Kazuyoshi
中科院分区：
文献类型：
--
作者：
Okuno, Yoshinori;Kitagawa, Yuuichi;Takeda, Kazuyoshi
采用聚乙烯-聚丙烯酸接枝聚合物（g-TEMPO）固定2,2,6,6-四甲基哌啶-1-氧（TEMPO），建立了一种用于伯醇和仲醇化学选择性氧化的三相（固-有机-水）连续流反应体系。在非混相流动条件下，g-TEMPO表现出比二氧化硅或交联聚苯乙烯负载的TEMPO更高的接触效率，并且在不损失催化活性的情况下保持了至少9天的良好转化。
We developed a triphasic (solid-organic-aqueous) continuous-flow reaction system for the chemoselective oxidation of primary and secondary alcohols, using 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) immobilized on polyethylene-g-polyacrylic acid graft polymer (g-TEMPO). g-TEMPO exhibited higher contact efficiency than TEMPO supported on silica or cross-linked polystyrene under immiscible-flow conditions, and maintained excellent conversion for at least 9 days with no loss of catalytic activity.