COMPARATIVE ACCURACY OF MAMMOGRAPHY AND ULTRASOUND IN WOMEN WITH BREAST SYMPTOMS ACCORDING TO AGE AND BREAST DENSITY
COMPARATIVE ACCURACY OF MAMMOGRAPHY AND ULTRASOUND IN WOMEN WITH BREAST SYMPTOMS ACCORDING TO AGE AND BREAST DENSITY
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DOI：
10.17305/bjbms.2009.2832
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发表时间：
2009-05-01
影响因子：
3.4
通讯作者：
Kutllovci, Arben
中科院分区：
文献类型：
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作者：
Devolli-Disha, Emine;Manxhuka-Kerliu, Suzana;Kutllovci, Arben
乳腺癌是最常见的癌症，也是妇女癌症死亡的第二大常见原因。本研究的目的是根据女性的年龄和乳腺密度来确定哪种成像测试更准确，乳房X光检查或超声诊断乳腺癌。我们对5、6例有乳腺症状的患者进行了临床乳腺检查、钼靶摄影和超声检查。通过组织病理学分析，共检查了546个乳腺病变。组织学结果显示259例浸润性癌和287例良性病变。敏感性随年龄和乳腺密度而变化。在259名同时接受两种检查的女性中，年龄小于45岁的女性超声检查的灵敏度高于乳房X线摄影，而年龄大于60岁的女性乳房X线摄影的灵敏度高于超声检查，乳房X线摄影的灵敏度根据年龄为52.1%，超声为72.6%。根据年龄，超声的特异性为88.5%，乳房X线摄影的特异性为73.9%。根据乳房密度比较乳房X线摄影和超声的灵敏度表明，乳房X线摄影的灵敏度在以脂肪乳房为主的女性中为82.2%，但在具有异质致密乳房的女性中为23.7%，随着乳腺密度的增加，乳房X线摄影的灵敏度水平降低，而超声检查在以脂肪乳腺为主的妇女中的敏感性为71.1%，在不均匀致密乳腺中的敏感性为57.0%。我们的数据表明，在有乳腺症状的患者中，超声的敏感性和特异性在统计学上显着高于乳房X线摄影，检测乳腺癌和良性病变，特别是在致密乳腺和年轻女性中。
Breast cancer is the most common cancer and the second most common cause of death from cancer in women. The aim Of this study was to determine which is more accurate imaging test mammography or ultrasound for diagnosis of breast cancer based on the women's age and breast density. We examined 5, 6 patients with breast symptoms, by clinical breast examination, mammography and ultrasound. A total of 546 breast lesions were examined by histopathology analyses. Histopathology results revealed the presence of 259 invasive cancers, and 287 benign lesions. Sensitivity varied significantly with age and breast density. In the 259 women who had both tests, ultrasound had a higher sensitivity than mammography in women Younger than 45 years, whereas mammography had a higher sensitivity than ultrasound ill women older than 60 years, The sensitivity according to age was 52,1% for mammography and 72,6% for ultrasound. The specificity according to age was 88, 5% for ultrasound and 73, 9% for mammography Comparing the sensitivity of mammography and ultrasound according to the breast density indicates that mammographic sensitivity was 82.2% among women with predominantly fatty breast, but 23.7% in women with heterogeneous dense breasts, with the increase of fibro glandular density the level of sensitivity with mammography decreases, while ultrasonographic sensitivity was 71,1% among women with predominantly fatty breast and 57,0% for heterogeneous dense breasts. Our data indicate that sensitivity and specificity of ultrasound was statistically significantly greater than mammography in patients with breast symptoms the detection of breast cancer and benign lesions particularly in dense breast and In young women.