Feasibility, Acceptability, and Preliminary Efficacy of a Smartphone Intervention for Schizophrenia
Feasibility, Acceptability, and Preliminary Efficacy of a Smartphone Intervention for Schizophrenia
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DOI：
10.1093/schbul/sbu033
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发表时间：
2014-11-01
影响因子：
6.6
通讯作者：
Mueser, Kim T.
中科院分区：
文献类型：
--
作者：
Ben-Zeev, Dror;Brenner, Christopher J.;Mueser, Kim T.
开发FOCUS智能手机干预是为了向精神分裂症患者提供自动化的实时/实时疾病管理支持。该系统专门设计用于可能有认知障碍、精神病症状、阴性症状和/或低阅读水平的精神病患者。FOCUS为用户提供即时和按需资源，以促进症状管理，情绪调节，药物依从性，社会功能和改善睡眠。在这项研究中，33名精神分裂症或情感障碍患者在自己的环境中使用FOCUS超过1个月。参与者能够学习如何独立使用干预措施，除一名参与者外，所有参与者都成功完成了试验，并完好无损地返回了智能手机。完成者在使用该设备的86.5%的日子里使用该系统，平均每天5.2次。大约62%的FOCUS干预的使用是由参与者发起的，38%的使用是对自动提示的响应。基线水平的认知功能，阴性症状，迫害意念，和阅读水平与参与者的干预使用无关。大约90%的参与者认为干预措施是高度可接受和可用的。配对样本t检验发现，FOCUS使用1个月后，精神病症状、抑郁症和一般精神病理学显著减少。本研究证明了FOCUS干预精神分裂症的可行性、可接受性和初步疗效，并介绍了一种新的治疗模式，该模式有望利用广泛可用的技术将循证护理的范围扩展到物理诊所之外。
The FOCUS smartphone intervention was developed to provide automated real-time/real-place illness management support to individuals with schizophrenia. The system was specifically designed to be usable by people with psychotic disorders who may have cognitive impairment, psychotic symptoms, negative symptoms, and/or low reading levels. FOCUS offers users both prescheduled and on-demand resources to facilitate symptom management, mood regulation, medication adherence, social functioning, and improved sleep. In this study, 33 individuals with schizophrenia or schizoaffective disorder used FOCUS over a 1-month period in their own environments. Participants were able to learn how to use the intervention independently, and all but one participant completed the trial successfully and returned the smartphones intact. Completers used the system on 86.5% of days they had the device, an average of 5.2 times a day. Approximately 62% of use of the FOCUS intervention was initiated by the participants, and 38% of use was in response to automated prompts. Baseline levels of cognitive functioning, negative symptoms, persecutory ideation, and reading level were not related to participants' use of the intervention. Approximately 90% of participants rated the intervention as highly acceptable and usable. Paired samples t tests found significant reductions in psychotic symptoms, depression, and general psychopathology, after 1 month of FOCUS use. This study demonstrated the feasibility, acceptability, and preliminary efficacy of the FOCUS intervention for schizophrenia and introduces a new treatment model which has promise for extending the reach of evidence-based care beyond the confines of a physical clinic using widely available technologies.