Imbalance between soluble tumour necrosis factor receptors type 1 and 2 in chronic periodontitis
Imbalance between soluble tumour necrosis factor receptors type 1 and 2 in chronic periodontitis
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DOI：
10.1111/j.1600-051x.2005.00832.x
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发表时间：
2005-10-01
影响因子：
6.7
通讯作者：
Yoshie, H
中科院分区：
文献类型：
--
作者：
Ikezawa, I;Tai, H;Yoshie, H
背景：可溶性 I 型和 2 型肿瘤坏死因子 (TNF) 受体调节慢性牙周炎 (CP) 中 TNF-α 介导的炎症反应。目的：本研究调查了健康受试者和 CP 患者龈沟液（GCF）和血清中 TNF-α、可溶性 TNF 受体 1 型和 2 型的水平。 材料和方法：收集了 16 名健康受试者和 22 名 CP 患者的 38 份血清和 73 份 GCF 样本。 GCF 是从探测口袋深度 (PPD) 收集的
Background: Soluble types of tumour necrosis factor (TNF) receptors type I and 2 modulate the TNF-alpha-mediated inflammatory responses in chronic periodontitis (CP). Objectives: This study investigated the levels of TNF-alpha, soluble TNF receptor type 1 and 2 in gingival crevicular fluid (GCF) and serum of healthy subjects and CP patients.Materials and Methods: Thirty-eight sera and 73 GCF samples were collected from 16 healthy subjects and 22 CP patients. GCF was collected from probing pocket depth (PPD)