Chromosome 1 localization of the human alpha-L-fucosidase structural gene with a homologous site on chromosome 2.
Chromosome 1 localization of the human alpha-L-fucosidase structural gene with a homologous site on chromosome 2.
复制标题
人类 α-L-岩藻糖苷酶结构基因在 1 号染色体上的定位，在 2 号染色体上有一个同源位点。
DOI：
10.1159/000132304
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Shows,TB
中科院分区：
文献类型：
--
作者：
Fowler,ML;Nakai,H;Byers,MG;Fukushima,H;Eddy,RL;Henry,WM;Haley,LL;O'Brien,JS;Shows,TB
Two cDNA clones coding for human α-L-fucosidase, one from the coding region and the other primarily from the 3’ untranslated region, were used to map the location of the α-L-fucosidase gene. Southern filter analysis of somatic cell hybrid lines mapped the structural gene to the short arm of human chromosome 1, and in situ hybridization to chromosomes of human leukocytes further localized the homologous area to the 1p36.1→p34.1 region, with the most likely location being the distal region of lp34. Further Southern filter analysis detected a second site of homology on chromosome 2. This α-L-fucosidase-like site has been designatedFUCA1L.
