Efficacy of continuous positive airway pressure in casualties suffering from primary blast lung injury: A modeling study.
Efficacy of continuous positive airway pressure in casualties suffering from primary blast lung injury: A modeling study.
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持续气道正压通气对原发性爆炸性肺损伤伤员的疗效：一项建模研究。
DOI：
10.1109/embc.2019.8857613
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Scott TE
中科院分区：
文献类型：
--
作者：
Scott TE
原发性冲击波肺损伤是由爆炸冲击波引起的多系统损伤综合征中最重要的组成部分。大多数这样的伤员需要在重症监护室进行通风。我们描述了一种新型的原发性冲击波肺损伤模拟器的使用，以评估持续气道正压通气的潜在疗效，在6个在硅片受伤后24小时。我们的研究结果表明，原发性冲击波肺损伤是一种急性肺损伤，可以有效地管理与持续气道正压通气。在严峻的环境中或在医疗资源不堪重负的情况下，使用环境空气的持续气道正压通气可能是有益的。
Primary blast lung injury is the most important component of a multisystem syndrome of injury that results from exposure to an explosive shockwave. The majority of such casualties require ventilation in an intensive care unit. We describe the use of a novel primary blast lung injury simulator to evaluate the potential efficacy of continuous positive airway pressure in 6 in silico casualties over 24 hours after injury. Our results suggest that primary blast lung injury is a form of acute lung injury that can be effectively managed with continuous positive airway pressure. In austere environments or in circumstances where medical resources are overwhelmed, continuous positive airway pressure using ambient air may be of benefit.