Randomised controlled trial of animal facilitated therapy with dolphins in the treatment of depression
Randomised controlled trial of animal facilitated therapy with dolphins in the treatment of depression
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DOI：
10.1136/bmj.331.7527.1231
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发表时间：
2005-11-26
影响因子：
105.7
通讯作者：
Reveley, MA
中科院分区：
文献类型：
--
作者：
Antonioli, C;Reveley, MA
目的评估动物促进疗法与海豚的有效性，控制自然环境的影响，在治疗轻度至中度抑郁症和在biophilia hypothesis.Setting背景下，这项研究是在洪都拉斯进行的，招募发生在美国和洪都拉斯。设计单盲，随机，对照试验。参与者门诊患者，结果30例患者随机分为两组，治疗组2例在第一周后退出，对照组3例在随机分配后撤回知情同意书。对于完成研究的参与者，治疗组的抑郁症状平均严重程度比对照组降低得更多（汉密尔顿抑郁量表，P = 0.002;贝克抑郁量表，P = 0.006）。对于通过修改的意向处理和末次观察值结转分析的样本，两组患者的汉密尔顿和Beck评分差异有统计学意义（分别为P = 0.007和P = 0.012）。海豚的动物促进疗法是一种有效的治疗轻度至中度抑郁症的方法，它是基于一种整体的方法，通过与自然界中的动物互动。
Objective To evaluate the effectiveness of animal facilitated therapy with dolphins, controlling for the influence of the natural setting, in the treatment of mild to moderate depression and in the context of the biophilia hypothesis.Setting The study was carried out in Honduras, and recruitment took place in the United States and Honduras.Design Single blind, randomised, controlled trial.Participants Outpatients, recruited through announcements on the internet, radio, newspapers, and hospitals.Results Of the 30 patients randomly assigned to the two groups of treatment, two dropped out of the treatment group after the first week and three withdrew their consent in the control group after they had been randomly allocated. For the participants who completed the study, the mean severity of the depressive symptoms was more reduced in the treatment group than in the control group (Hamilton rating scale for depression, P = 0.002; Beck depression inventory, P = 0.006). For the sample analysed by modified intention to treat and last observation carried forward, the mean differences for die. Hamilton and Beck scores between the two groups was highly significant (P = 0.007 and P = 0.012, respectively).Conclusions The therapy was effective in alleviating symptoms of depression after two weeks of treatment. Animal facilitated therapy with dolphins is an effective treatment for mild to moderate depression, which is based on a holistic approach, through interaction with animals in nature.