Mycobacterium avium complex – the role of potable water in disease transmission
Mycobacterium avium complex – the role of potable water in disease transmission
复制标题
鸟分枝杆菌复合体——饮用水在疾病传播中的作用
DOI：
10.1111/j.1365-2672.2012.05298.x
复制
发表时间：
2012
影响因子：
4
通讯作者：
R. Bentham
中科院分区：
文献类型：
--
作者：
Harriet Whiley;A. Keegan;S. Giglio;R. Bentham
鸟分枝杆菌复合群（MAC）是一组重要的公共卫生问题的机会致病菌。它负责广泛的疾病，取决于亚种，感染途径和患者预先存在的疾病。目前，关于MAC感染的发病率的研究有限，这些研究考虑了肺部和其他临床表现。MAC已从各种陆地和水生环境中分离出来，包括天然沃茨、工程水系统和土壤。查明造成人类感染的具体环境来源对于尽量减少疾病流行至关重要。本文回顾了目前的文献和案例研究，关于MAC引起的疾病的广谱性和饮用水在疾病传播中的作用。饮用水被认为是MAC感染的假定途径。与人类感染有关的受污染饮用水源包括热水分配系统、淋浴、抽水马桶、家庭饮用水、游泳池和热水浴缸。MAC可通过其对消毒剂的高抗性、与生物膜的关联以及自由生活的原生动物的细胞内寄生来维持饮用水源的长期污染。需要进一步的研究来调查水处理过程对MAC的效率，以及热水分配系统的建设和维护，以及它们在MAC扩散中所起的作用。
Mycobacterium avium complex (MAC) is a group of opportunistic pathogens of major public health concern. It is responsible for a wide spectrum of disease dependent on subspecies, route of infection and patients pre‐existing conditions. Presently, there is limited research on the incidence of MAC infection that considers both pulmonary and other clinical manifestations. MAC has been isolated from various terrestrial and aquatic environments including natural waters, engineered water systems and soils. Identifying the specific environmental sources responsible for human infection is essential in minimizing disease prevalence. This paper reviews current literature and case studies regarding the wide spectrum of disease caused by MAC and the role of potable water in disease transmission. Potable water was recognized as a putative pathway for MAC infection. Contaminated potable water sources associated with human infection included warm water distribution systems, showers, faucets, household drinking water, swimming pools and hot tub spas. MAC can maintain long‐term contamination of potable water sources through its high resistance to disinfectants, association with biofilms and intracellular parasitism of free‐living protozoa. Further research is required to investigate the efficiency of water treatment processes against MAC and into construction and maintenance of warm water distribution systems and the role they play in MAC proliferation.
过敏性肺炎：基于人群的研究中高分辨率 CT 的敏感性。
DOI：
10.2214/ajr.159.3.1503007
发表时间：
1992
期刊：
AJR. American journal of roentgenology
影响因子：
--
作者：
Lynch,DA;Rose,CS;Way,D;KingJr,TE
通讯作者：
KingJr,TE
DOI：
10.1164/rccm.200207-678oc
发表时间：
2003-03-15
影响因子：
24.7
作者：
Olivier, KN;Weber, DJ;Knowles, MR
通讯作者：
Knowles, MR