Imaging polarimetry in patients with neovascular age-related macular degeneration
Imaging polarimetry in patients with neovascular age-related macular degeneration
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DOI:
10.1364/josaa.24.001468
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发表时间:
2007-05-01
影响因子:
1.9
通讯作者:
Miura, Masahiro
中科院分区:
文献类型:
--
作者:
Elsner, Ann E.;Weber, Anke;Miura, Masahiro
Imaging polarimetry was used to examine different components of neovascular membranes in age-related macular degeneration. Retinal images were acquired with a scanning laser polarimeter. An innovative pseudo-color scale, based on cardinal directions of color, displayed two types of image information: relative phases and magnitudes of birefringence. Membranes had relative phase changes that did not correspond to anatomical structures in reflectance images. Further, membrane borders in depolarized light images had significantly higher contrasts than those in reflectance images. The retinal birefringence in neovascular membranes indicates optical activity consistent with molecular changes rather than merely geometrical changes. (C) 2007 Optical Society of America.