Drifting codes within a stable coding scheme for working memory
Drifting codes within a stable coding scheme for working memory
复制标题
工作记忆稳定编码方案中的漂移代码
DOI:
10.1101/714311
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发表时间:
2019
期刊:
影响因子:
--
通讯作者:
Wolff M
中科院分区:
文献类型:
--
作者:
Wolff M
Working memory (WM) is important to maintain information over short time periods to provide some stability in a constantly changing environment. However, brain activity is inherently dynamic, raising a challenge for maintaining stable mental states. To investigate the relationship between WM stability and neural dynamics, we used electroencephalography to measure the neural response to impulse stimuli during a WM delay. Multivariate pattern analysis revealed representations were both stable and dynamic: there was a clear difference in neural states between time-specific impulse responses, reflecting dynamic changes, yet the coding scheme for memorised orientations was stable. This suggests that a stable subcomponent in WM enables stable maintenance within a dynamic system. A stable coding scheme simplifies readout for WM-guided behaviour, whereas the low-dimensional dynamic component could provide additional temporal information. Despite having a stable subspace, WM is clearly not perfect—memory performance still degrades over time. Indeed, we find that even within the stable coding scheme, memories drift during maintenance. When averaged across trials, such drift contributes to the width of the error distribution.
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DOI:
10.1523/jneurosci.1194-19.2019
发表时间:
2019-11
期刊:
The Journal of Neuroscience
影响因子:
--
作者:
Michael J. Wolff;G. Kandemir;M. Stokes;Elkan G. Akyürek
通讯作者:
Michael J. Wolff;G. Kandemir;M. Stokes;Elkan G. Akyürek
DOI:
--
发表时间:
2019
期刊:
bioRxiv
影响因子:
--
作者:
Michael J. Wolff;Michael J. Wolff;G. Kandemir;M. Stokes;Elkan G. Akyürek
通讯作者:
Elkan G. Akyürek
影响因子:
9.8
作者:
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通讯作者:
Maass W
DOI:
10.1523/jneurosci.3577-09.2009
发表时间:
2009-11-04
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Brouwer GJ;Heeger DJ
通讯作者:
Heeger DJ
DOI:
--
发表时间:
2018
期刊:
bioRxiv
影响因子:
--
作者:
Christopher J. Cueva;Encarni Marcos;A. Saez;A. Genovesio;M. Jazayeri;M. Jazayeri;R. Romo;C. Salzman;M. Shadlen;Stefano Fusi
通讯作者:
Stefano Fusi