Breathing-based leg exercises during hemodialysis improve quality of life: A randomized controlled trial
Breathing-based leg exercises during hemodialysis improve quality of life: A randomized controlled trial
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DOI：
10.1177/02692155211000738
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发表时间：
2021-04-08
影响因子：
3
通讯作者：
Liao, Tzu-Yi
中科院分区：
文献类型：
--
作者：
Huang, Hsin-Yi;Hung, Kuo-Sheng;Liao, Tzu-Yi
目的：评价为期12周的以呼吸为基础的腿部运动对稳定心率变异性和减轻疲劳的常规血液透析患者生活质量的影响。设计：随机对照试验。环境：台湾北部某医疗中心有94张床位的血液透析科。参与者：86名接受血液透析的终末期肾病患者被招募并随机分配到ExBr组或对照组。干预措施：以呼吸为基础的腿部锻炼项目包括腹部呼吸和低强度的腿部锻炼，包括腿部提升、股四头肌收缩和膝关节屈曲，每次持续15分钟，每周三次，持续12周。主要测量方法：在基线和第4周、第8周和第12周，使用世界卫生组织生活质量评估简表、心率变异性生理信号记录仪和血液透析相关疲劳量表收集数据。结果：ExBr组平均（标准差）年龄为53.70（10.04）岁，对照组平均（标准差）年龄为61.19（10.19）岁。校正年龄、肌酐、心率变异性和疲劳的线性混合模型显示，ExBr组患者的生活质量显著高于对照组（P = 0.01），特别是在第12周（P = 0.04）。疲劳与生活质量显著相关（P < 0.001）。结论：本研究支持血液透析期间持续以呼吸为基础的腿部运动至少12周的益处，它改善了终末期肾病患者的生活质量，并且不影响其生命体征的稳定性。
Objective:To evaluate the effect of a 12-week breathing-based leg exercises program on quality of life under stabilizing heart rate variability and reducing fatigue in regular hemodialysis patients.Design:Randomized controlled trial.Setting:A 94-bed hemodialysis department at a medical center in northern Taiwan.Participants:Eighty-six patients with end-stage renal disease undergoing hemodialysis were recruited and randomly assigned to the ExBr or control groups.Interventions:The breathing-based leg exercises program comprised abdominal breathing and low-intensity leg exercise, including leg lifts, quadriceps femoris contraction and knee flexion, and lasted for 15 minutes at one time, three times a week for 12 weeks.Main measure:Data was collected by using the World Health Organization quality of life assessment-brief, physiological signal recorder for heart rate variability and hemodialysis-related fatigue scale at baseline and on Week 4, Week 8, and Week 12.Results:Average (standard deviation) age was 53.70 (10.04) years in the ExBr group and 61.19 (10.19) years in the control group. The linear mixed model with adjusted age, creatinine, heart rate variability and fatigue revealed that the ExBr group had significantly higher quality of life than did the control group (P = 0.01), especially on Week 12 (P = 0.04). Fatigue was significantly correlated with quality of life (P < 0.001).Conclusion:This study supported the benefits of the continued breathing-based leg exercises during hemodialysis for at least 12 weeks, which improved the quality of life of patients with end-stage renal disease and did not affect the stability of their vital signs.